Product Name
ALDH16A1, Polyclonal Antibody
Full Product Name
ALDH16A1 Antibody - N-terminal region
Product Gene Name
anti-ALDH16A1 antibody
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Antibody/Peptide Pairs
ALDH16A1 peptide (MBS3242346) is used for blocking the activity of ALDH16A1 antibody (MBS3217450)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: YGPVPESHAC ALAWLDTQDR CLGHYVNGKW LKPEHRNSVP CQDPITGENL
3D Structure
ModBase 3D Structure for Q8IZ83
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 79%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human ALDH16A1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ALDH16A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALDH16A1 antibody
This is a rabbit polyclonal antibody against ALDH16A1. It was validated on Western Blot
Target Description: This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-ALDH16A1 antibody
Polyclonal; Disease Related;
Applications Tested/Suitable for anti-ALDH16A1 antibody
Western Blot (WB)
Western Blot (WB) of anti-ALDH16A1 antibody
Host: Rabbit
Target Name: ALDH16A1
Sample Type: ACHN Whole Cell lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for ALDH16A1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001138868.1
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NCBI GenBank Nucleotide #
NM_001145396.1
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UniProt Primary Accession #
Q8IZ83
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UniProt Related Accession #
Q8IZ83[Other Products]
NCBI Official Full Name
aldehyde dehydrogenase family 16 member A1 isoform 2
NCBI Official Synonym Full Names
aldehyde dehydrogenase 16 family member A1
NCBI Official Symbol
ALDH16A1??[Similar Products]
NCBI Protein Information
aldehyde dehydrogenase family 16 member A1
UniProt Protein Name
Aldehyde dehydrogenase family 16 member A1
Protein Family
Aldehyde dehydrogenase family
UniProt Gene Name
ALDH16A1??[Similar Products]
UniProt Entry Name
A16A1_HUMAN
NCBI Summary for ALDH16A1
This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
UniProt Comments for ALDH16A1
Subunit structure: Interacts with SPG21. Ref.5
Sequence similarities: Belongs to the aldehyde dehydrogenase family.
Caution: The active site cysteine and glutamate residues are not conserved in this protein. Its activity is therefore unsure.
Sequence caution: The sequence AAH35641.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB84962.1 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.
Research Articles on ALDH16A1
1. Both the short and long forms of human ALDH16A1 protein would lack catalytic activity.
Precautions
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Disclaimer
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