Full Product Name
SAR1B (SAR1 homolog B (S. cerevisiae), ANDD, CMRD, GTBPB, GTP-binding protein Sara, SARA2, SARB, SAR1a gene homolog 2)
Product Synonym Names
Anti -SAR1B (SAR1 homolog B (S. cerevisiae), ANDD, CMRD, GTBPB, GTP-binding protein Sara, SARA2, SARB, SAR1a gene homolog 2)
Product Gene Name
anti-SAR1B antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 2; NC_010444.3 (142463692..142489104, complement). Location: chromosome: 2
3D Structure
ModBase 3D Structure for Q5PYH3
Species Reactivity
Mouse, Rat
Specificity
Recognizes mouse SAR1B at~25kD. Species sequence homology: human.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Immunogen
Synthetic peptide, C-DHERLLESKEELD, from the internal region of mouse SAR1B.
Positive Control
Mouse Liver and Rat Liver lysates
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 monthsat -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-SAR1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SAR1B antibody
SAR1B is involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
Product Categories/Family for anti-SAR1B antibody
Antibodies; Abs to Transport Proteins
Applications Tested/Suitable for anti-SAR1B antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SAR1B antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:8000
Western Blot: 0.03-0.1ug/ml
NCBI/Uniprot data below describe general gene information for SAR1B. It may not necessarily be applicable to this product.
NCBI Accession #
ABM66369.1
[Other Products]
UniProt Primary Accession #
Q5PYH3
[Other Products]
UniProt Secondary Accession #
Q4ZJK0[Other Products]
UniProt Related Accession #
Q5PYH3[Other Products]
Molecular Weight
22,382 Da[Similar Products]
NCBI Official Full Name
Sara2 protein
NCBI Official Symbol
SAR1B??[Similar Products]
NCBI Official Synonym Symbols
GTBPB; SARA2
??[Similar Products]
NCBI Protein Information
GTP-binding protein SAR1b; SAR1 gene homolog B; SAR1a gene homolog 2
UniProt Protein Name
GTP-binding protein SAR1b
Protein Family
GTP-binding protein
UniProt Gene Name
SAR1B??[Similar Products]
UniProt Entry Name
SAR1B_PIG
UniProt Comments for SAR1B
Function: Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex
By similarity.
Subunit structure: Homodimer. Binds PREB. Part of the COPII coat complex. Binds to the cytoplasmic tails of target proteins in the endoplasmic reticulum
By similarity.
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein
By similarity. Golgi apparatus ? Golgi stack membrane; Peripheral membrane protein
By similarity. Note: Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region
By similarity.
Sequence similarities: Belongs to the small GTPase superfamily. SAR1 family.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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