For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Affinity Purified

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-ATP2A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This is a rabbit polyclonal antibody against ATP2A1. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to

Polyclonal; Membrane Protein; Tissue Specific & Cell Marker;

Immunohistochemistry (IHC), Western Blot (WB)

Sample Type :
Rhesus macaque spinal cord
Primary Antibody Dilution :
1:300
Secondary Antibody :
Donkey anti Rabbit 488
Secondary Antibody Dilution :
1:500
Color/Signal Descriptions :
Green: ATP2A1
Gene Name :
ATP2A1
Submitted by :
Timur Mavlyutov, Ph. D., Department of Pharmacology, University of Wisconsin Medical School, 1300 University Avenue, Madison, WI 53706

WB Suggested Anti-ATP2A1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: THP-1 cell lysate

109kDa

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Putative uncharacterized protein DKFZp779O2152

Q7Z675_HUMAN

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Oct 2013]

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