Product Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (HSD3B), Recombinant Protein
Full Product Name
Recombinant Horse 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (HSD3B)
Product Gene Name
HSD3B recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-373aa; full length protein
Sequence
AGWSCLVTGA GGFLGQRIVR LLVEEKEVQE IRALDKVFRP ELREEFSKLQ SKVKLTVLEG DILDEQFLKR ACQGASAVIH TASIIDVTNL FNPQVTMNVN VEGTQLLLEA CSQASVPIFI YTSSVAVAGP NSYREIIQNG HEEAHLETKW SSPYPYSKKL AEKAVLAANG LPLKNGGTLY TCALRPMFIY GEGSPTLYYL MHEGLNNNGI LTHNCKFSRA NPVYVGNIAW AHIMALRALR DPKKAPSIQG QFYYISDDTP PQSYDDLTYT LSKKWGFCLD SRMRLPIFLK YWLAFLLEIV SFLLSPIYKY RPPFDRHLVT WQNSVFTFSY KKAQRDMGYE PLFSWEEAKK RTTEWIDALV EPHQEALKTK TL
3D Structure
ModBase 3D Structure for O46516
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HSD3B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for HSD3B recombinant protein
Transmembrane Protein
Application Notes for HSD3B recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for HSD3B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001075380.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001081911.1
[Other Products]
UniProt Primary Accession #
O46516
[Other Products]
UniProt Secondary Accession #
P79437[Other Products]
UniProt Related Accession #
O46516[Other Products]
Molecular Weight
42,411 Da
NCBI Official Full Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
NCBI Official Symbol
HSD3B2??[Similar Products]
NCBI Official Synonym Symbols
HSD3B; HSD3B1; 3-beta-HSD
??[Similar Products]
NCBI Protein Information
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
UniProt Protein Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
UniProt Synonym Protein Names
3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC:1.1.1.145)Alternative name(s):3-beta-hydroxy-5-ene steroid dehydrogenase; Progesterone reductase
Protein Family
4-isomerase" title="3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase">3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
UniProt Gene Name
HSD3B??[Similar Products]
UniProt Synonym Gene Names
3-beta-HSD??[Similar Products]
UniProt Entry Name
3BHS_HORSE
UniProt Comments for HSD3B
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
