Product Name
B3GALTL, Polyclonal Antibody
Full Product Name
B3GALTL Antibody
Product Synonym Names
B3GLCT; B3GTL; B3Glc-T; Gal-T; beta3Glc-T
Product Gene Name
anti-B3GALTL antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of B3GALTL
Calculated Molecular Weight: 57kd
Observed Molecular Weight: 57kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-B3GALTL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-B3GALTL antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-B3GALTL antibody
WB: 1:200-1:2000
IHC: 1:20-1:200
Testing Data of anti-B3GALTL antibody
NCBI/Uniprot data below describe general gene information for B3GALTL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_919299.3
[Other Products]
NCBI GenBank Nucleotide #
NM_194318.3
[Other Products]
UniProt Secondary Accession #
Q5W0H2; Q6NUI3; A8K5F8[Other Products]
UniProt Related Accession #
Q6Y288[Other Products]
Molecular Weight
56,564 Da
NCBI Official Full Name
beta-1,3-glucosyltransferase
NCBI Official Synonym Full Names
beta 1,3-galactosyltransferase-like
NCBI Official Symbol
B3GALTL??[Similar Products]
NCBI Official Synonym Symbols
B3GTL; Gal-T; B3GLCT; B3Glc-T; beta3Glc-T
??[Similar Products]
NCBI Protein Information
beta-1,3-glucosyltransferase; UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like; beta 3-glycosyltransferase-like; beta-3-glycosyltransferase-like
UniProt Protein Name
Beta-1,3-glucosyltransferase
UniProt Synonym Protein Names
Beta-3-glycosyltransferase-like
UniProt Gene Name
B3GALTL??[Similar Products]
UniProt Synonym Gene Names
B3GTL; Beta3Glc-T??[Similar Products]
UniProt Entry Name
B3GLT_HUMAN
NCBI Summary for B3GALTL
The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009]
UniProt Comments for B3GALTL
B3GALTL: O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. Defects in B3GALTL are the cause of Peters-plus syndrome (PpS). PpS is an autosomal recessive disorder characterized by anterior eye-chamber abnormalities, disproportionate short stature, developmental delay, characteristic craniofacial features, cleft lip and/or palate. Belongs to the glycosyltransferase 31 family.
Protein type: Transferase; EC 2.4.1.-; Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q12.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: transferase activity, transferring glycosyl groups
Biological Process: fucose metabolic process; protein amino acid O-linked glycosylation; cellular protein metabolic process; post-translational protein modification
Disease: Peters-plus Syndrome
Research Articles on B3GALTL
1. G splicing mutation within the B3GALTL gene in typical Peters-plus syndrome">a novel c.597-2 A>G splicing mutation within the B3GALTL gene in typical Peters-plus syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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