Product Name
B3GALTL, Blocking Peptide
Full Product Name
B3GALTL Blocking Peptide
Product Synonym Names
B3GTL; Beta-1,3-glucosyltransferase; Beta3Glc-T; Beta-3-glycosyltransferase-like
Product Gene Name
B3GALTL blocking peptide
[Similar Products]
B3GALTL peptide (MBS8243533) is used for blocking the activity of B3GALTL antibody (MBS8242756)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6Y288
Form/Format
Lyophilized Powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of B3GALTL blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
B3GALTL blocking peptide
The peptide is used to block Anti-B3GALTL Antibody reactivity.
Applications Tested/Suitable for B3GALTL blocking peptide
Blocking (BL)
Application Notes for B3GALTL blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for B3GALTL. It may not necessarily be applicable to this product.
NCBI Accession #
Q6Y288.2
[Other Products]
UniProt Primary Accession #
Q6Y288
[Other Products]
UniProt Secondary Accession #
Q5W0H2; Q6NUI3; A8K5F8[Other Products]
UniProt Related Accession #
Q6Y288[Other Products]
Molecular Weight
56,564 Da
NCBI Official Full Name
Beta-1,3-glucosyltransferase
NCBI Official Synonym Full Names
beta 3-glucosyltransferase
NCBI Official Symbol
B3GLCT??[Similar Products]
NCBI Official Synonym Symbols
B3GTL; Gal-T; B3GALTL; B3Glc-T; beta3Glc-T
??[Similar Products]
NCBI Protein Information
beta-1,3-glucosyltransferase
UniProt Protein Name
Beta-1,3-glucosyltransferase
UniProt Synonym Protein Names
Beta 3-glucosyltransferase
UniProt Gene Name
B3GLCT??[Similar Products]
UniProt Synonym Gene Names
Beta3Glc-T??[Similar Products]
UniProt Entry Name
B3GLT_HUMAN
NCBI Summary for B3GALTL
The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009]
UniProt Comments for B3GALTL
B3GALTL: O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. Defects in B3GALTL are the cause of Peters-plus syndrome (PpS). PpS is an autosomal recessive disorder characterized by anterior eye-chamber abnormalities, disproportionate short stature, developmental delay, characteristic craniofacial features, cleft lip and/or palate. Belongs to the glycosyltransferase 31 family.
Protein type: EC 2.4.1.-; Transferase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q12.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: transferase activity, transferring glycosyl groups
Biological Process: cellular protein metabolic process; fucose metabolic process; post-translational protein modification; protein amino acid O-linked glycosylation
Disease: Peters-plus Syndrome
Research Articles on B3GALTL
1. POFUT2 and B3GLCT mediate a noncanonical endoplasmic reticulum quality-control mechanism that recognizes folded thrombospondin type 1 repeats and stabilizes them by glycosylation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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