Product Name
Atf7ip, Blocking Peptide
Full Product Name
Atf7ip Peptide - middle region
Product Gene Name
Atf7ip blocking peptide
[Similar Products]
Product Synonym Gene Name
2610204M12Rik; AM; Mcaf1[Similar Products]
Atf7ip peptide (MBS3228481) is used for blocking the activity of Atf7ip antibody (MBS3203513)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MSTPEGEKSE KDGKAEEEER VPAEEQPPVR NEFSRRKRSK SEDMDSVESK
3D Structure
ModBase 3D Structure for Q7TT18
Species Reactivity
Mouse, Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of Atf7ip blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Atf7ip blocking peptide
This is a synthetic peptide designed for use in combination with anti-Atf7ip Antibody, made
Target Description: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Atf7ip may have ATPase activity.
Product Categories/Family for Atf7ip blocking peptide
Peptide
Applications Tested/Suitable for Atf7ip blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for Atf7ip. It may not necessarily be applicable to this product.
NCBI Accession #
NP_062299
[Other Products]
NCBI GenBank Nucleotide #
NM_019426
[Other Products]
UniProt Primary Accession #
Q7TT18
[Other Products]
UniProt Related Accession #
Q7TT18[Other Products]
NCBI Official Full Name
activating transcription factor 7-interacting protein 1
NCBI Official Synonym Full Names
activating transcription factor 7 interacting protein
NCBI Official Symbol
Atf7ip??[Similar Products]
NCBI Official Synonym Symbols
AM; Mcaf1; 2610204M12Rik
??[Similar Products]
NCBI Protein Information
activating transcription factor 7-interacting protein 1
UniProt Protein Name
Activating transcription factor 7-interacting protein 1
UniProt Synonym Protein Names
ATFa-associated modulator; mAM; MBD1-containing chromatin-associated factor 1
Protein Family
Activating transcription factor 7-interacting protein
UniProt Gene Name
Atf7ip??[Similar Products]
UniProt Synonym Gene Names
Mcaf1; mAM??[Similar Products]
UniProt Entry Name
MCAF1_MOUSE
Research Articles on Atf7ip
1. We demonstrated the importance of Aire's interaction with the ATF7ip-MBD1 protein complex in maintaining central tolerance
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
