Full Product Name
CD9 antibody - N-terminal region
Product Gene Name
anti-CD9 antibody
[Similar Products]
Product Synonym Gene Name
5H9; BA2; BTCC-1; DRAP-27; GIG2; MIC3; MRP-1; P24; TSPAN29; TSPAN-29[Similar Products]
Antibody/Peptide Pairs
CD9 peptide (MBS3240026) is used for blocking the activity of CD9 antibody (MBS3215111)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: KYLLFGFNFI FWLAGIAVLA IGLWLRFDSQ TKSIFEQETN NNNSSFYTGV
3D Structure
ModBase 3D Structure for P21926
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 86%; Dog: 92%; Goat: 93%; Guinea Pig: 77%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 86%; Rat: 100%; Sheep: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CD9
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CD9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD9 antibody
This is a rabbit polyclonal antibody against CD9. It was validated on Western Blot
Target Description: This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.
Product Categories/Family for anti-CD9 antibody
Polyclonal; Various;
Applications Tested/Suitable for anti-CD9 antibody
Western Blot (WB)
Western Blot (WB) of anti-CD9 antibody
Sample Type: Human Fetal heart
CD9 antibody - N-terminal region validated by WB using Fetal Heart Lysate at 1.0ug/ml.
Western Blot (WB) of anti-CD9 antibody
Sample Type: mouse fibroblast lusate (10ug)
Primary Dilution: 1:2000 (1% BSA)
Secondary Dilution: 1:2000 (5% milk)
Image Submitted By:
Anonymous researcher
NCBI/Uniprot data below describe general gene information for CD9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001760
[Other Products]
NCBI GenBank Nucleotide #
NM_001769
[Other Products]
UniProt Primary Accession #
P21926
[Other Products]
UniProt Related Accession #
P21926[Other Products]
NCBI Official Full Name
CD9 antigen isoform 1
NCBI Official Synonym Full Names
CD9 molecule
NCBI Official Symbol
CD9??[Similar Products]
NCBI Official Synonym Symbols
MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29
??[Similar Products]
NCBI Protein Information
CD9 antigen
UniProt Protein Name
CD9 antigen
UniProt Synonym Protein Names
5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24
Protein Family
CD9 antigen
UniProt Gene Name
CD9??[Similar Products]
UniProt Synonym Gene Names
MIC3; TSPAN29; MRP-1; Tspan-29??[Similar Products]
UniProt Entry Name
CD9_HUMAN
NCBI Summary for CD9
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
UniProt Comments for CD9
CD9: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family.
Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: extracellular space; platelet alpha granule membrane; focal adhesion; integral to plasma membrane; apical plasma membrane; plasma membrane; vesicle; external side of plasma membrane
Molecular Function: integrin binding; protein binding
Biological Process: negative regulation of cell proliferation; platelet activation; platelet degranulation; fusion of sperm to egg plasma membrane; single fertilization; pathogenesis; brain development; cell adhesion; cell motility; blood coagulation; oligodendrocyte development; response to water deprivation; multicellular organism reproduction; paranodal junction assembly
Research Articles on CD9
1. Our findings indicate an important role of CD9 for lentiviral vector and exosome biogenesis and point out a remarkable function of this tetraspanin in membrane fusion, viral infectivity, and exosome-mediated horizontal information transfer.
Precautions
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Disclaimer
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