Full Product Name
ADCK4 antibody
Product Gene Name
anti-ADCK4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 141 and 430 of Human ADCK4
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.
Other Notes
Small volumes of anti-ADCK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-ADCK4 antibody
Total protein Ab
Applications Tested/Suitable for anti-ADCK4 antibody
Western Blot (WB)
Application Notes for anti-ADCK4 antibody
Western blotting: 1:500-1:3000
Testing Data of anti-ADCK4 antibody
Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE Primary antibody diluted at 1: 1000
NCBI/Uniprot data below describe general gene information for ADCK4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_079152
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NCBI GenBank Nucleotide #
NM_024876.3
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UniProt Secondary Accession #
Q8TAJ1; Q9HA52[Other Products]
UniProt Related Accession #
Q96D53[Other Products]
Molecular Weight
55,853 Da
NCBI Official Full Name
aarF domain-containing protein kinase 4 isoform a
NCBI Official Synonym Full Names
aarF domain containing kinase 4
NCBI Official Symbol
ADCK4??[Similar Products]
NCBI Official Synonym Symbols
NPHS9
??[Similar Products]
NCBI Protein Information
aarF domain-containing protein kinase 4
UniProt Protein Name
AarF domain-containing protein kinase 4
UniProt Gene Name
ADCK4??[Similar Products]
UniProt Entry Name
ADCK4_HUMAN
NCBI Summary for ADCK4
This gene encodes a protein with two copies of a domain found in protein kinases. The encoded protein has a complete protein kinase catalytic domain, and a truncated domain that contains only the active and s of the protein kinase domain, however, it is not known whether the protein has any kinase activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
UniProt Comments for ADCK4
ADCK4: The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). Belongs to the protein kinase superfamily. ADCK protein kinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; EC 2.7.11.-; EC 2.7.-.-; Kinase, protein; Protein kinase, atypical; Protein kinase, Ser/Thr (non-receptor); ATYPICAL group; ABC1 family; ABC1-A subfamily
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: mitochondrial membrane; plasma membrane; integral to membrane; cytosol
Molecular Function: protein serine/threonine kinase activity
Biological Process: protein amino acid phosphorylation
Disease: Nephrotic Syndrome, Type 9
Research Articles on ADCK4
1. Mutations in ADCK4 resulted in reduced CoQ10 levels and reduced mitochondrial respiratory enzyme activity in cells isolated from individuals with steroid-resistant nephrotic syndrome & transformed lymphoblasts.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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