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CD9, Blocking Peptide

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產(chǎn)品名稱: CD9, Blocking Peptide
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CD9, Blocking Peptide


CD9, Blocking Peptide  的詳細介紹
Product Name

CD9, Blocking Peptide

Full Product Name

CD9 Antibody (Center) Blocking Peptide

Product Synonym Names
CD9 antigen; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD9; CD9; MIC3; TSPAN29
Product Gene Name

CD9 blocking peptide

[Similar Products]
Product Synonym Gene Name
MIC3; TSPAN29[Similar Products]
Antibody/Peptide Pairs
CD9 peptide (MBS9221141) is used for blocking the activity of CD9 antibody (MBS9202019)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
143030
3D Structure
ModBase 3D Structure for P21926
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human CD9. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location
Detected in platelets (at protein level). Expressed by a variety of hematopoietic and epithelial cells
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of CD9 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
CD9 blocking peptide
Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.
NCBI/Uniprot data below describe general gene information for CD9. It may not necessarily be applicable to this product.
NCBI GI #
231724
NCBI GeneID
928
NCBI Accession #
P21926.4 [Other Products]
UniProt Primary Accession #
P21926 [Other Products]
UniProt Secondary Accession #
Q5J7W6; Q96ES4; D3DUQ9[Other Products]
UniProt Related Accession #
P21926[Other Products]
Molecular Weight
25,416 Da
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NCBI Official Full Name
CD9 antigen
NCBI Official Synonym Full Names
CD9 molecule
NCBI Official Symbol
CD9??[Similar Products]
NCBI Official Synonym Symbols
MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29
??[Similar Products]
NCBI Protein Information
CD9 antigen
UniProt Protein Name
CD9 antigen
UniProt Synonym Protein Names
5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD_antigen: CD9
Protein Family
CD9 antigen
UniProt Gene Name
CD9??[Similar Products]
UniProt Synonym Gene Names
MIC3; TSPAN29; MRP-1; Tspan-29??[Similar Products]
UniProt Entry Name
CD9_HUMAN
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NCBI Summary for CD9
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
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UniProt Comments for CD9
CD9: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family.

Protein type: Cell adhesion; Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: extracellular space; focal adhesion; membrane; plasma membrane; platelet alpha granule membrane

Molecular Function: protein binding

Biological Process: cell adhesion; cell motility; cell surface receptor linked signal transduction; fusion of sperm to egg plasma membrane; paranodal junction assembly; platelet degranulation; receptor internalization
Research Articles on CD9
1. Collectively, using tetraspanin CD9 in tandem with E-cadherin as a biomarker in renal cell carcinoma will help to not only distinguish between types, but also predict the metastatic potential of RCC.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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