Product Name
ASMT, cDNA Clone
Full Product Name
ASMT cDNA Clone
Product Gene Name
ASMT cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgggatcct cagaggacca ggcctatcgc ctccttaatg actacgccaa cggcttcatg gtgtcccagg ttctcttcgc cgcctgcgag ctgggcgtgt ttgaccttct cgccgaggcc ccagggcccc tggacgtggc ggcagtggct gcaggtgtga gggccagcgc ccatgggaca gagctcctgc tggacatctg tgtgtccctg aagctgctga aagtggagac gaggggagga aaagctttct atcgaaacac agagctgtcc agcgactacc tgaccacggt cagcccgacg tcacaatgca gcatgctgaa gtacatgggc aggaccagct accggtgctg gggccacctg gcagacgccg tgagagaagg aaggaaccag tacctggaga cgtttggcgt tcccgctgaa gagcttttta cggccatcta caggtccgag ggcgagcggc tacagttcat gcaagctctg caggaggtct ggagcgtcaa cgggagaagc gtgctgaccg cctttgacct gtcagtgttc ccacttatgt gtgaccttgg tggggatttc ttcaaagacc ctcttccgga agctgatctg tacatcctgg ccagggtcct ccatgactgg gcagatggaa agtgctcaca cctgctggag aggatctacc acacttgcaa gccaggtggt ggcattctgg taattgaaag cctcctggat gaagacaggc gaggtcctct gctcacgcag ctctactctc tgaacatgct tgtgcagacg gaagggcagg agaggacccc cacccactac cacatgctcc tctcttctgc tggcttcaga gacttccagt ttaagaaaac aggagccatt tatgatgcca ttttagccag gaaataa
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ASMT cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ASMT. It may not necessarily be applicable to this product.
NCBI Accession #
BC001620
[Other Products]
UniProt Secondary Accession #
Q16598; Q5JQ72; Q5JQ73; B2RC33[Other Products]
UniProt Related Accession #
P46597[Other Products]
Molecular Weight
41,661 Da
NCBI Official Full Name
Homo sapiens acetylserotonin O-methyltransferase, mRNA
NCBI Official Synonym Full Names
acetylserotonin O-methyltransferase
NCBI Official Symbol
ASMT??[Similar Products]
NCBI Official Synonym Symbols
ASMTY; HIOMT; HIOMTY
??[Similar Products]
NCBI Protein Information
acetylserotonin O-methyltransferase
UniProt Protein Name
Acetylserotonin O-methyltransferase
UniProt Synonym Protein Names
Hydroxyindole O-methyltransferase; HIOMT
Protein Family
Acetylserotonin O-methyltransferase
UniProt Gene Name
ASMT??[Similar Products]
UniProt Synonym Gene Names
HIOMT??[Similar Products]
UniProt Entry Name
ASMT_HUMAN
NCBI Summary for ASMT
This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]
UniProt Comments for ASMT
ASMT: Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin. Belongs to the methyltransferase superfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tryptophan; Methyltransferase; EC 2.1.1.4
Chromosomal Location of Human Ortholog: Xp22.3 or Yp11.3
Cellular Component: cytosol
Molecular Function: acetylserotonin O-methyltransferase activity; identical protein binding; O-methyltransferase activity; protein homodimerization activity; S-methyltransferase activity
Biological Process: indolalkylamine biosynthetic process; melatonin biosynthetic process; translation
Research Articles on ASMT
1. two single nucleotide polymorphisms (rs4446909 and rs5989681)in the promoter of ASMT do not contribute to the pathogenesis of schizophrenia in Chinese-Han subjects
Precautions
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Disclaimer
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