Product Name
Disks large 1 tumor suppressor protein (dlg1), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Disks large 1 tumor suppressor protein (dlg1), partial
Product Gene Name
dlg1 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P31007
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of dlg1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for dlg1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001096955.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001103485.3
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UniProt Primary Accession #
P31007
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UniProt Secondary Accession #
Q7KV38; Q7KV39; Q7KV40; Q7YXH8; Q8SY37; Q8T0C6; A4V4A8; A4V4B0; A8JUR9; A8JUS0; C7LAH6[Other Products]
UniProt Related Accession #
P31007[Other Products]
Molecular Weight
104,263 Da
NCBI Official Full Name
discs large 1, isoform K
NCBI Official Synonym Full Names
discs large 1
NCBI Official Symbol
dlg1??[Similar Products]
NCBI Official Synonym Symbols
11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; DmelCG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)
??[Similar Products]
NCBI Protein Information
CG1725 gene product from transcript CG1725-RL
UniProt Protein Name
Disks large 1 tumor suppressor protein
Protein Family
Disks large
UniProt Gene Name
dlg1??[Similar Products]
UniProt Synonym Gene Names
l(1)dlg1??[Similar Products]
UniProt Comments for dlg1
During embryonic development, some isoforms are essential for proper neuronal differentiation and organization. Required for cell polarity; maintenance of apicobasal polarity. Plays a critical role at septate junctions in cellular growth control during larval development. The presence of a guanylate kinase domain suggests involvement in cellular adhesion as well as signal transduction to control cellular proliferation.
Research Articles on dlg1
1. Exon junction complex (EJC) activity is indispensable for Wg signaling by maintaining an appropriate level of Dsh protein for Wg ligand reception in Drosophila. Genetic and biochemical experiments demonstrate that Dlg1 protein acts independently from its role in cell polarity to protect Dsh protein from lysosomal degradation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
