Product Name
11-cis retinol dehydrogenase (RDH5), Recombinant Protein
Full Product Name
Recombinant Bovine 11-cis retinol dehydrogenase (RDH5)
Product Gene Name
RDH5 recombinant protein
[Similar Products]
Product Synonym Gene Name
RDH5[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
24-318aa, Full Length of Mature Protein
Sequence
LPASDAFIFI TGCDSGFGRL LALRLDQRGF RVLASCLTPS GAEDLQRVAS SRLHTTLLDV TDPQSIRQAV KWVETHVGEA GLFGLVNNAG VAGIIGPTPW QTREDFQRVL NVNTLGPIGV TLALLPLLLQ ARGRVINITS VLGRLAANGG GYCVSKFGLE AFSDSLRRDV APFGVRVSIV EPGFFRTPVT NLETLEDTLQ ACWARLPPAT QALYGEAFLT KYLRVQQRIM NMICDPDLAK VSRCLEHALT ARHPRTRYSP GWDAKLLWLP ASYLPARLVD AVLAWVLPKP AQTVY
3D Structure
ModBase 3D Structure for Q27979
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of RDH5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RDH5 recombinant protein
This gene encodes an enzyme belonging to the short-chain dehydrogenases
reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments.
NCBI/Uniprot data below describe general gene information for RDH5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_776591.2
[Other Products]
NCBI GenBank Nucleotide #
NM_174166.3
[Other Products]
UniProt Primary Accession #
Q27979
[Other Products]
UniProt Secondary Accession #
Q28004; F1ML51[Other Products]
UniProt Related Accession #
Q27979[Other Products]
Molecular Weight
35,037 Da
NCBI Official Full Name
11-cis retinol dehydrogenase
NCBI Official Synonym Full Names
retinol dehydrogenase 5
NCBI Official Symbol
RDH5??[Similar Products]
NCBI Official Synonym Symbols
P32; 9cRDH
??[Similar Products]
NCBI Protein Information
11-cis retinol dehydrogenase
UniProt Protein Name
11-cis retinol dehydrogenase
UniProt Synonym Protein Names
9-cis retinol dehydrogenase; 9cRDH; P32
Protein Family
11-cis retinol dehydrogenase
UniProt Gene Name
RDH5??[Similar Products]
UniProt Synonym Gene Names
RDH1; 11-cis RDH; 11-cis RoDH; 9cRDH??[Similar Products]
UniProt Comments for RDH5
Stereospecific 11-cis retinol dehydrogenase, which catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments. Also able to oxidize 9-cis-retinol and 13-cis-retinol, but not all-trans-retinol. Active in the presence of NAD as cofactor but not in the presence of NADP.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
