Goat Polyclonal to Human RDH1/RDH5; RDH5; 11-cis retinol dehydrogenase; 9cRDH; 11-cis RDH; Retinol dehydrogenase 1; SDR9C5; HSD17B9; RDH1

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Goat

Human RDH5.

Immunoaffinity Purified

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Store at -20 degree C.
Avoid freeze-thaw cycles.

Small volumes of anti-RDH1/RDH5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

RDH1/RDH5 is an enzyme belonging to the short-chaindehydrogenases/reductases (SDR) family. This retinol dehydrogenasefunctions to catalyze the final step in the biosynthesis of 11-cisretinaldehyde, which is the universal chromophore of visual pigments.Mutations in this gene cause autosomal recessive fundus albipunctatus, arare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments.

ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)

ELISA: 1:8000
IHC-P: 5 ug/ml
WB: 2-4 ug/ml

Anti-RDH1/RDH5 antibody IHC staining of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

RDH5 antibody (2 ug/ml) staining of Mouse Eye lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

34,979 Da

retinol dehydrogenase 5

11-cis retinol dehydrogenase

11-cis retinol dehydrogenase

HSD17B9; RDH1; SDR9C5; 11-cis RDH; 11-cis RoDH; 9cRDH??[Similar Products]

This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]

Stereospecific 11-cis retinol dehydrogenase, which catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments. Also able to oxidize 9-cis-retinol and 13-cis-retinol, but not all-trans-retinol. Active in the presence of NAD as cofactor but not in the presence of NADP.

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