Full Product Name
RDH5 Antibody (Rabbit Polyclonal)
Product Gene Name
anti-RDH5 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human
Predicted: Rat, Mouse
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-RDH5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RDH5 antibody
Rabbit polyclonal RDH5 (1) antibody was raised against a recombinate human RDH5 protein 109-307aa (BC028298).
Applications Tested/Suitable for anti-RDH5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RDH5 antibody
ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:100-1:500
NCBI/Uniprot data below describe general gene information for RDH5. It may not necessarily be applicable to this product.
NCBI Accession #
BC028298
[Other Products]
UniProt Secondary Accession #
O00179; Q8TAI2[Other Products]
UniProt Related Accession #
Q92781[Other Products]
Molecular Weight
34,979 Da
NCBI Official Full Name
Homo sapiens retinol dehydrogenase 5 (11-cis/9-cis), mRNA
NCBI Official Synonym Full Names
retinol dehydrogenase 5
NCBI Official Symbol
RDH5??[Similar Products]
NCBI Official Synonym Symbols
RDH1; 9cRDH; SDR9C5; HSD17B9
??[Similar Products]
NCBI Protein Information
11-cis retinol dehydrogenase
UniProt Protein Name
11-cis retinol dehydrogenase
UniProt Synonym Protein Names
9-cis retinol dehydrogenase; 9cRDH; Retinol dehydrogenase 5; Short chain dehydrogenase/reductase family 9C member 5
Protein Family
11-cis retinol dehydrogenase
UniProt Gene Name
RDH5??[Similar Products]
UniProt Synonym Gene Names
HSD17B9; RDH1; SDR9C5; 11-cis RDH; 11-cis RoDH; 9cRDH??[Similar Products]
NCBI Summary for RDH5
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]
UniProt Comments for RDH5
Stereospecific 11-cis retinol dehydrogenase, which catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments. Also able to oxidize 9-cis-retinol and 13-cis-retinol, but not all-trans-retinol. Active in the presence of NAD as cofactor but not in the presence of NADP.
Research Articles on RDH5
1. We conclude that the expression of Rlbp1 and Rdh5 critically depends on functional Mitf in the RPE and suggest that MITF has an important role in controlling retinoid processing in the RPE.
Precautions
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Disclaimer
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