极品新婚夜少妇真紧,亚洲精品一区二区三区中文字幕 ,久久久久人妻精品一区三寸蜜桃,日韩人妻无码一区二区三区

產(chǎn)品資料

Cellular tumor antigen p53 (TP53), Recombinant Protein

如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: Cellular tumor antigen p53 (TP53), Recombinant Protein
產(chǎn)品型號:
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

Cellular tumor antigen p53 (TP53), Recombinant Protein


Cellular tumor antigen p53 (TP53), Recombinant Protein  的詳細(xì)介紹
Product Name

Cellular tumor antigen p53 (TP53), Recombinant Protein

Full Product Name

Recombinant Bovine Cellular tumor antigen p53 (TP53)

Product Gene Name

TP53 recombinant protein

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
TOP
Sequence Positions
1-386aa, Full length protein
Sequence
MEESQAELNV EPPLSQETFS DLWNLLPENN LLSSELSAPV DDLLPYTDVA TWLDECPNEA PQMPEPSAPA APPPATPAPA TSWPLSSFVP SQKTYPGNYG FRLGFLQSGT AKSVTCTYSP SLNKLFCQLA KTCPVQLWVD SPPPPGTRVR AMAIYKKLEH MTEVVRRCPH HERSSDYSDG LAPPQHLIRV EGNLRAEYLD DRNTFRHSVV VPYESPEIDS ECTTIHYNFM CNSSCMGGMN RRPILTIITL EDSCGNLLGR NSFEVRVCAC PGRDRRTEEE NLRKKGQSCP EPPPRSTKRA LPTNTSSSPQ PKKKPLDGEY FTLQIRGFKR YEMFRELNDA LELKDALDGR EPGESRAHSS HLKSKKRPSP SCHKKPMLKR EGPDSD
3D Structure
ModBase 3D Structure for P67939
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Bovine
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of TP53 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
TOP
Related Product Information for
TP53 recombinant protein
This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it s believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53- and activate expression of downstream genes that inhibit growth and
or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA , and hence cause the loss of tumor suppressor activity. Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome. Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found. These variants encode distinct isoforms, which can regulate p53 transcriptional activity.
NCBI/Uniprot data below describe general gene information for TP53. It may not necessarily be applicable to this product.
NCBI GI #
28849929
NCBI GeneID
281542
NCBI Accession #
NP_776626.1 [Other Products]
NCBI GenBank Nucleotide #
NM_174201.2 [Other Products]
UniProt Primary Accession #
P67939 [Other Products]
UniProt Secondary Accession #
Q29628; Q3ZCF1[Other Products]
UniProt Related Accession #
P67939[Other Products]
Molecular Weight
43,256 Da
TOP
NCBI Official Full Name
cellular tumor antigen p53
NCBI Official Synonym Full Names
tumor protein p53
NCBI Official Symbol
TP53??[Similar Products]
NCBI Protein Information
cellular tumor antigen p53
UniProt Protein Name
Cellular tumor antigen p53
UniProt Synonym Protein Names
Tumor suppressor p53
Protein Family
Cellular tumor antigen
UniProt Gene Name
TP53??[Similar Products]
TOP
TOP
UniProt Comments for TP53
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
Research Articles on TP53
1. The effect of p53 expression on the development of cloned embryos, and its interaction with HDAC1 and DNMT3A are reported.
TOP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
TOP
TOP
產(chǎn)品留言
標(biāo)題
聯(lián)系人
聯(lián)系電話
內(nèi)容
驗證碼
點擊換一張
注:1.可以使用快捷鍵Alt+S或Ctrl+Enter發(fā)送信息!
2.如有必要,請您留下您的詳細(xì)聯(lián)系方式!
相關(guān)產(chǎn)品
PDGF-AA, ELISA Kit
PDGF-AA, ELISA Kit
PDGF-AA, ELISA Kit
PDGF-AA, ELISA Kit
PDGF-AA, ELISA Kit
PDGF-AA, ELISA Kit
PDGF-AA, ELISA Kit
Microphthalmia Associated Transcription Factor (MITF), ELISA Kit
microphthalmia-associated transcription factor, Polyclonal Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, Blocking Peptide
CYP1B1, Polyclonal Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, Polyclonal Antibody
CYP1B1, cDNA Clone
CYP1B1, Antibody
Cytochrome P450 1B1, Antibody
Cytochrome P450 1B1, Polyclonal Antibody
Cytochrome P450 1B1, Polyclonal Antibody
Cytochrome P450 1B1, Antibody
Cytochrome P450 1B1, Antibody
Cytochrome P450 1B1 (CYP1B1), Polyclonal Antibody
Cytochrome P450 1B1 (CYP1B1), Polyclonal Antibody
Cytochrome P450 1B1 (CYP1B1), Polyclonal Antibody
Cytochrome P450 1B1 (CYP1B1), Polyclonal Antibody
Cytochrome P450 1B1 (CYP1B1), Polyclonal Antibody
Cytochrome P450 1B1 (CYP1B1), Polyclonal Antibody
Cytochrome P450 1B1 (CYP1B1), ELISA Kit
Cytochrome P450 1B1 (CYP1B1), ELISA Kit
Cytochrome P450 1B1 (CYP1B1), ELISA Kit
Cytochrome P450 1B1 (CYP1B1), ELISA Kit
Cytochrome P450 1B1 (CYP1B1), Antibody Pair Kit
Cytochrome P450 1B1 (CYP1B1), Active Protein
Cytochrome P450 1B1 (CYP1B1), Polyclonal Antibody
Cytochrome P450 1B1 (CYP1B1), RTU ELISA Kit
Cytochrome P450 1B1 (CYP1B1), Recombinant Protein
Optineurin, Polyclonal Antibody
AGPAT2, Polyclonal Antibody
AGPAT2, cDNA Clone
AGPAT2, cDNA Clone
AGPAT2, Polyclonal Antibody
AGPAT2, Polyclonal Antibody
AGPAT2, Blocking Peptide
AGPAT2, cDNA Clone

滬公網(wǎng)安備 31011202007343號