Product Name
dihydropyrimidinase (DPYS), ELISA Kit
Full Product Name
Rat Dihydropyrimidinase, DPYS ELISA Kit
Product Synonym Names
Rat Dihydropyrimidinase (DPYS) ELISA kit; DHP; DHPase; dihydropyrimidine amidohydrolase; hydantoinase; dihydropyrimidinase
Product Gene Name
DPYS elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q63150
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of DPYS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for DPYS purchase
MBS9318605 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the dihydropyrimidinase (DPYS) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DPYS. The ELISA analytical biochemical technique of the MBS9318605 kit is based on DPYS antibody-DPYS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DPYS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DPYS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for DPYS. It may not necessarily be applicable to this product.
NCBI Accession #
NP_113893.1
[Other Products]
NCBI GenBank Nucleotide #
NM_031705.1
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UniProt Primary Accession #
Q63150
[Other Products]
UniProt Secondary Accession #
Q642F0[Other Products]
UniProt Related Accession #
Q63150[Other Products]
Molecular Weight
56,815 Da
NCBI Official Full Name
dihydropyrimidinase
NCBI Official Synonym Full Names
dihydropyrimidinase
NCBI Official Symbol
Dpys??[Similar Products]
NCBI Protein Information
dihydropyrimidinase; DHP; DHPase; hydantoinase; dihydropyrimidine amidohydrolase
UniProt Protein Name
Dihydropyrimidinase
UniProt Synonym Protein Names
Dihydropyrimidine amidohydrolase; Hydantoinase
Protein Family
Dihydropyrimidinase
UniProt Gene Name
Dpys??[Similar Products]
UniProt Synonym Gene Names
DHP; DHPase??[Similar Products]
UniProt Entry Name
DPYS_RAT
NCBI Summary for DPYS
enzyme thatcatalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism [RGD, Feb 2006]
UniProt Comments for DPYS
DPYS: Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6- dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. Defects in DPYS are the cause of dihydropyrimidinase deficiency (DHPD). DHPD is an autosomal recessive disorder characterized by dihydropyrimidinuria and associated with a variable clinical phenotype: epileptic or convulsive attacks, dysmorphic features and severe developmental delay, and congenital microvillous atrophy. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Protein type: Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; Other Amino Acids Metabolism - beta-alanine; EC 3.5.2.2; Hydrolase
Cellular Component: cytosol
Molecular Function: thymine binding; amino acid binding; dihydropyrimidinase activity; uracil binding; zinc ion binding; phosphoprotein binding
Biological Process: uracil metabolic process; beta-alanine metabolic process; uracil catabolic process; thymine catabolic process; pyrimidine base catabolic process; protein homooligomerization; protein homotetramerization
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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