Product Name
beta I Tubulin (TUBB1), Polyclonal Antibody
Full Product Name
Anti-beta I Tubulin Rabbit pAb
Product Synonym Names
Beta tubulin 1; class VI; Class VI beta tubulin antibody; TBB1_HUMAN; TUBB1; Tubulin beta 1 class VI; Tubulin; beta 1 antibody
Product Gene Name
anti-TUBB1 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H4B7
Species Reactivity
Human, Mouse, Rat, Cow, Dog, Monkey
Specificity
beta I Tubulin Antibody detects endogenous levels of total beta I Tubulin
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human beta I Tubulin
Subcellular Location
Cytoplasm; Cytoskeleton
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Other Notes
Small volumes of anti-TUBB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TUBB1 antibody
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).
Applications Tested/Suitable for anti-TUBB1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes for anti-TUBB1 antibody
WB: 1:3000-1:10000
IHC: 1:100-1:200
ICC/IF: 1:100-1:200
FC/FACS: 1:100
Western Blot (WB) of anti-TUBB1 antibody
Western blot analysis of beta I Tubulin expression in (1) K562 cell lysate; (2) Jurkat cell lysate; (3) HeLa cell lysate; (4) 293T cell lysate using beta I Tubulin antibody.
Immunohistochemistry (IHC) of anti-TUBB1 antibody
Immunohistochemical analysis of paraffin-embedded human tonsil, using beta I Tubulin Antibody.
Immunofluorescence (IF) of anti-TUBB1 antibody
Immunofluorescent analysis of Hela cells, using beta I Tubulin Antibody.
NCBI/Uniprot data below describe general gene information for TUBB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_110400.1
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NCBI GenBank Nucleotide #
NM_030773.3
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UniProt Primary Accession #
Q9H4B7
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UniProt Related Accession #
Q9H4B7[Other Products]
Molecular Weight
50kDa[Similar Products]
NCBI Official Full Name
tubulin beta-1 chain
NCBI Official Synonym Full Names
tubulin beta 1 class VI
NCBI Official Symbol
TUBB1??[Similar Products]
NCBI Protein Information
tubulin beta-1 chain
UniProt Protein Name
Tubulin beta-1 chain
UniProt Gene Name
TUBB1??[Similar Products]
NCBI Summary for TUBB1
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010]
UniProt Comments for TUBB1
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain ().
Research Articles on TUBB1
1. novel DCX mutation (p.D90G, NP_000546.2) appeared to be a major causative variant, whereas the novel mutation of TUBB1 (p.R62fsX, NP_110400.1) was found only in patients with more-severe intellectual disability in Familial pachygyria
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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