Product Name
Glycogen debranching enzyme (AGL), Protein
Full Product Name
Glycogen debranching enzyme
Product Synonym Names
GDE; Glycogen debrancher
Product Gene Name
AGL protein
[Similar Products]
Matching Pairs
Antibody: AGL (MBS2897551)
Antigen: Glycogen debranching enzyme (MBS2889266)
Matching Pairs
Antibody: AGL (MBS2897552)
Antigen: Glycogen debranching enzyme (MBS2889266)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2889266 Technical Datasheet
Technical Datasheet PDF
Sequence Positions
1-240aa
3D Structure
ModBase 3D Structure for P35573
Purity/Purification
>95% by SDS-PAGE
Endotoxin Level
<0.10 EU per 1 mug of the protein by the LAL method
Storage Buffer
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Preparation and Storage
Store at -20 degree C.
Avoid repeated freezing and thawing.
Other Notes
Small volumes of AGL protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for AGL protein
ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array
NCBI/Uniprot data below describe general gene information for AGL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000019.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000028.2
[Other Products]
UniProt Primary Accession #
P35573
[Other Products]
UniProt Secondary Accession #
P78354; P78544; Q59H92; Q6AZ90; Q9UF08; A6NCX7; A6NEK2; D3DT51[Other Products]
UniProt Related Accession #
P35573[Other Products]
Molecular Weight
172,696 Da
NCBI Official Full Name
glycogen debranching enzyme isoform 1
NCBI Official Synonym Full Names
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
NCBI Official Symbol
AGL??[Similar Products]
NCBI Official Synonym Symbols
GDE
??[Similar Products]
NCBI Protein Information
glycogen debranching enzyme
UniProt Protein Name
Glycogen debranching enzyme
UniProt Synonym Protein Names
Glycogen debrancherIncluding the following 2 domains:4-alpha-glucanotransferase (EC:2.4.1.25)Alternative name(s):Oligo-1,4-1,4-glucantransferase
Protein Family
Glycogen debranching enzyme
UniProt Gene Name
AGL??[Similar Products]
UniProt Synonym Gene Names
GDE; Amylo-1,6-glucosidase??[Similar Products]
NCBI Summary for AGL
This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for AGL
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
Research Articles on AGL
1. The study identified 31 novel mutations and extended the mutation spectrum of AGL in Chinese patients with glycogen storage disease type III.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
