Product Name
beta I tubulin (TUBB1), Monclonal Antibody
Full Product Name
Anti-beta I tubulin Mouse mAb
Product Synonym Names
2810484G07Rik; Beta tubulin 1; class VI; Class VI beta tubulin; dJ543J19.4; M(beta)1; TBB1_HUMAN; TUBB1; Tubulin beta 1 class VI; Tubulin beta-1 chain; Tubulin; beta 1; tubulin; beta1
Product Gene Name
anti-TUBB1 antibody
[Similar Products]
Product Synonym Gene Name
POLR3A[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H4B7
Species Reactivity
Human, Rat, Mouse
Purity/Purification
Affinity Purified
Form/Format
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Immunogen
Synthetic Peptide of beta I tubulin.
Subcellular Location
Cytoplasm; Cytoskeleton
Other Notes
Small volumes of anti-TUBB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-TUBB1 antibody
Western Blot (WB)
Application Notes for anti-TUBB1 antibody
WB: 1:500-10000
IF: 1:200
IHC: 1:50-300
Western Blot (WB) of anti-TUBB1 antibody
Western blot detection of beta I Tubulin in CHO-K1, Jurkat, 3T3, C6 and Hela cell lysates using beta I Tubulin mouse mAb (1:100000 diluted).Predicted band size:55kDa.Observed band size:55kDa.
Western Blot (WB) of anti-TUBB1 antibody
Western blot analysis of 1) Hela, 2) Mouse Brain Tissue, 3) Rat Brain Tissue, diluted at 1:5000.
NCBI/Uniprot data below describe general gene information for TUBB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_110400.1
[Other Products]
NCBI GenBank Nucleotide #
NM_030773.3
[Other Products]
UniProt Primary Accession #
Q9H4B7
[Other Products]
UniProt Related Accession #
Q9H4B7[Other Products]
NCBI Official Full Name
tubulin beta-1 chain
NCBI Official Synonym Full Names
tubulin beta 1 class VI
NCBI Official Symbol
TUBB1??[Similar Products]
NCBI Protein Information
tubulin beta-1 chain
UniProt Protein Name
Tubulin beta-1 chain
UniProt Gene Name
TUBB1??[Similar Products]
NCBI Summary for TUBB1
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010]
UniProt Comments for TUBB1
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain ().
Research Articles on TUBB1
1. novel DCX mutation (p.D90G, NP_000546.2) appeared to be a major causative variant, whereas the novel mutation of TUBB1 (p.R62fsX, NP_110400.1) was found only in patients with more-severe intellectual disability in Familial pachygyria
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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