Anti -GABA(B) Receptor 1, phosphorylated (Ser923) (Gamma-aminobutyric Acid (GABA) B Receptor 1, Gamma-aminobutyric Acid Type B Receptor Subunit 1, GABA B Receptor 1, GABABR1, GABA-B-R1, GABA-BR1, GABBR1-3, Gb1, GBR1) (Azide Free)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 6; NC_000006.11 (29570005..29600962, complement). Location: 6p21.31

Polyclonal

IgG

Rabbit

Recognizes rat GABR1 when phosphorylated at Ser923. Species sequence homology: Mouse, Primate, Human, Bovine.

Affinity Purified
Purified by immunoaffinity chromatography.

Supplied as a liquid in 10mM Hepes, pH 7.5, 0.09% sodium azide, 0.01% BSA, 50% glycerol.

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Small volumes of anti-GABBR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Antibodies; Abs to Receptors

Western Blot (WB)

Suitable for use in Western Blot.
Dilution: Western Blot: 1:1000

95,134 Da[Similar Products]

gamma-aminobutyric acid (GABA) B receptor, 1

gamma-aminobutyric acid type B receptor subunit 1; GABA-BR1; GABAB, subunit 1c; OTTHUMP00000029114; OTTHUMP00000029115; OTTHUMP00000029116; OTTHUMP00000109099; OTTHUMP00000214725; seven transmembrane helix receptor

Gamma-aminobutyric acid (GABA) B receptor 1 isoform b variant

Q53EM0_HUMAN

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq]

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