Mouse EF-hand domain-containing protein 1 (EFHC1) ELISA kit; EJA1; EJM; EJM1; FLJ10466; FLJ37290; JAE; dJ304B14.2; ; EF-hand domain (C-terminal) containing 1

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of EFHC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9318733 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the EF-hand domain (C-terminal) containing 1 (EFHC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EFHC1. The ELISA analytical biochemical technique of the MBS9318733 kit is based on EFHC1 antibody-EFHC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EFHC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EFHC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

75,142 Da

EF-hand domain (C-terminal) containing 1

EF-hand domain-containing protein 1; myoclonin-1

EF-hand domain-containing protein 1

EFHC1_MOUSE

EFHC1: microtubule-associated protein (MAP) that is abundant in sperm flagella and motile cilia but expressed at low levels in the ***** brain. It is not present in immotile primary cilia. May enhance calcium influx through CACNA1E and stimulate programmed cell death. Interacts with the C-terminus of CACNA1E. Implicated in neuronal migration and may play a role during brain development. Mutations in EFHC1 gene have been previously reported in patients with epilepsies, including those with juvenile myoclonic epilepsy. Two alternatively spliced human isoforms have been described.

Cellular Component: centrosome; cytoskeleton; cell soma; cell; cytoplasm; axoneme; cilium

Molecular Function: protein C-terminus binding; calcium ion binding

Biological Process: cellular calcium ion homeostasis; cerebral cortex cell migration; positive regulation of apoptosis

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