Full Product Name
HBA1 Polyclonal Antibody
Product Synonym Names
HBA-T3; HBH
Product Gene Name
anti-HBA1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MVLSPADKTN VKAAWGKVGA HAGEYGAEAL ERMFLSFPTT KTYFPHFDLS HGSAQVKGHG KKVADALTNA VAHVDDMPNA LSALSDLHAH KLRVDPVNFK
3D Structure
ModBase 3D Structure for P69905
Purity/Purification
Affinity Purification
Immunogen
A synthetic peptide of human HBA1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-HBA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HBA1 antibody
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal ***** life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of ***** hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Product Categories/Family for anti-HBA1 antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-HBA1 antibody
Western Blot (WB)
Application Notes for anti-HBA1 antibody
WB: 1:500 - 1:2000
NCBI/Uniprot data below describe general gene information for HBA1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000508.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000517.4
[Other Products]
UniProt Primary Accession #
P69905
[Other Products]
UniProt Secondary Accession #
P01922; Q1HDT5; Q3MIF5; Q53F97; Q96KF1; Q9NYR7; Q9UCM0[Other Products]
UniProt Related Accession #
P69905[Other Products]
NCBI Official Full Name
hemoglobin subunit alpha
NCBI Official Synonym Full Names
hemoglobin subunit alpha 2
NCBI Official Symbol
HBA2??[Similar Products]
NCBI Official Synonym Symbols
HBH; HBA-T2
??[Similar Products]
NCBI Protein Information
hemoglobin subunit alpha
UniProt Protein Name
Hemoglobin subunit alpha
UniProt Synonym Protein Names
Alpha-globin; Hemoglobin alpha chain
Protein Family
Hemoglobin
UniProt Gene Name
HBA1??[Similar Products]
NCBI Summary for HBA1
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal ***** life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of ***** hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for HBA1
Involved in oxygen transport from the lung to the various peripheral tissues.
Research Articles on HBA1
1. In this paper, the experimental results of resonance Raman, terahertz time-domain, and 1H nuclear magnetic resonance spectroscopy for the Hb M are described in detail. The heterogeneity of alpha subunits, which has been observed previously, is reconfirmed, and its implications for the dynamical structure of the alpha2beta2 tetramer and the regulation of O2 affinity are discussed.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
