Full Product Name
HBA2 Antibody
Product Gene Name
anti-HBA2 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P69905
Other Notes
Small volumes of anti-HBA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-HBA2 antibody
Western blot analysis HBA2 using Jurkat whole cell lysates
NCBI/Uniprot data below describe general gene information for HBA2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000508.1
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NCBI GenBank Nucleotide #
NM_000517.4
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UniProt Primary Accession #
P69905
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UniProt Secondary Accession #
P01922; Q1HDT5; Q3MIF5; Q53F97; Q96KF1; Q9NYR7; Q9UCM0[Other Products]
UniProt Related Accession #
P69905[Other Products]
Molecular Weight
15,258 Da
NCBI Official Full Name
hemoglobin subunit alpha
NCBI Official Synonym Full Names
hemoglobin subunit alpha 2
NCBI Official Symbol
HBA2??[Similar Products]
NCBI Official Synonym Symbols
HBH; HBA-T2
??[Similar Products]
NCBI Protein Information
hemoglobin subunit alpha
UniProt Protein Name
Hemoglobin subunit alpha
UniProt Synonym Protein Names
Alpha-globin; Hemoglobin alpha chain
UniProt Gene Name
HBA1??[Similar Products]
NCBI Summary for HBA2
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal ***** life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of ***** hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for HBA2
Involved in oxygen transport from the lung to the various peripheral tissues.
Research Articles on HBA2
1. A) within the conserved CCAAT box of beta-globin gene has been identified in heterozygous state. The proband and his two relatives carrying the same mutation showed almost normal mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) level and slightly elevated HbA2.">In this study, a novel promoter mutation of -72 (T-->A) within the conserved CCAAT box of beta-globin gene has been identified in heterozygous state. The proband and his two relatives carrying the same mutation showed almost normal mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) level and slightly elevated HbA2.
Precautions
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