Full Product Name
BOLA2 Antibody, HRP conjugated
Product Synonym Names
BolA-like protein 2; BOLA2; BOLA2A; My016; AND; BOLA2B
Product Gene Name
anti-BOLA2 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H3K6
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human BolA-like protein 2 protein (1-86AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-BOLA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BOLA2 antibody
Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (PubMed:26613676, PubMed:27519415). Acts together with the monothiol glutaredoxin GLRX3 (PubMed:26613676, PubMed:27519415).
Product Categories/Family for anti-BOLA2 antibody
Others
Applications Tested/Suitable for anti-BOLA2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for BOLA2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001026997.1
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NCBI GenBank Nucleotide #
NM_001031827.2
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UniProt Primary Accession #
Q9H3K6
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UniProt Secondary Accession #
A1L454; A7YDY3[Other Products]
UniProt Related Accession #
Q9H3K6[Other Products]
Molecular Weight
6,842 Da
NCBI Official Full Name
bolA-like protein 2 isoform 1
NCBI Official Synonym Full Names
bolA family member 2
NCBI Official Symbol
BOLA2??[Similar Products]
NCBI Official Synonym Symbols
My016; BOLA2A; BOLA2B
??[Similar Products]
NCBI Protein Information
bolA-like protein 2
UniProt Protein Name
BolA-like protein 2
Protein Family
BolA-like protein
UniProt Gene Name
BOLA2??[Similar Products]
UniProt Synonym Gene Names
BOLA2A??[Similar Products]
NCBI Summary for BOLA2
This gene is located within a region of a segmental duplication on chromosome 16 and is identical to BOLA2B (bolA family member 2B). The product of this gene belongs to a family of proteins that are widely conserved and may be involved in iron maturation. Related pseudogenes are found multiple different chromosomes. Alternative splicing results in multiple transcript variants. Transcripts initiating at this locus may extend into downstream SMG1 pseudogene 6 (SMG1P6) and encode fusion proteins with a C-terminus related to SMG1 phosphatidylinositol 3-kinase-related kinase. A readthrough locus is represented with GeneID:107282092. [provided by RefSeq, Feb 2016]
UniProt Comments for BOLA2
Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (PubMed:26613676, PubMed:27519415). Acts together with the monothiol glutaredoxin GLRX3 (PubMed:26613676, PubMed:27519415).
Research Articles on BOLA2
1. The Glrx3 and BolA2 bound and facilitated Fe-S incorporation into Ciapin1, a [2Fe-2S] protein functioning early in the cytosolic Fe-S assembly pathway. Thus, Glrx3.BolA is a [2Fe-2S] chaperone complex capable of transferring [2Fe-2S] clusters to apoproteins in human cells.
Precautions
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Disclaimer
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