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14-3-3 protein zeta/delta (Ywhaz), Recombinant Protein

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產(chǎn)品名稱: 14-3-3 protein zeta/delta (Ywhaz), Recombinant Protein
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14-3-3 protein zeta/delta (Ywhaz), Recombinant Protein


14-3-3 protein zeta/delta (Ywhaz), Recombinant Protein  的詳細(xì)介紹
Product Name

14-3-3 protein zeta/delta (Ywhaz), Recombinant Protein

Full Product Name

Recombinant Mouse 14-3-3 protein zeta/delta (Ywhaz)

Product Synonym Names
Protein kinase C inhibitor protein 1
Product Gene Name

Ywhaz recombinant protein

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
Full Length, 1-245aa
3D Structure
ModBase 3D Structure for P63101
Host
E Coli
Species Reactivity
Mouse
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Tag Info
N-terminal 6xHis-SUMO-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Other Notes
Small volumes of Ywhaz recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
Ywhaz recombinant protein
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
NCBI/Uniprot data below describe general gene information for Ywhaz. It may not necessarily be applicable to this product.
NCBI GI #
359385696
NCBI GeneID
22631
NCBI Accession #
NP_001240734.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001253805.1 [Other Products]
UniProt Primary Accession #
P63101 [Other Products]
UniProt Secondary Accession #
P35215; P70197; P97286; Q3TSF1; Q5EBQ1[Other Products]
UniProt Related Accession #
P63101[Other Products]
Molecular Weight
43.75 kDa
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NCBI Official Full Name
14-3-3 protein zeta/delta isoform 1
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
NCBI Official Symbol
Ywhaz??[Similar Products]
NCBI Official Synonym Symbols
AI596267; AL022924; AU020854; 14-3-3zeta; 1110013I11Rik
??[Similar Products]
NCBI Protein Information
14-3-3 protein zeta/delta
UniProt Protein Name
14-3-3 protein zeta/delta
UniProt Synonym Protein Names
Protein kinase C inhibitor protein 1; KCIP-1; SEZ-2
Protein Family
14-3-3 protein
UniProt Gene Name
Ywhaz??[Similar Products]
UniProt Synonym Gene Names
KCIP-1??[Similar Products]
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UniProt Comments for Ywhaz
14-3-3 zeta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Phosphorylation apparently disrupts homodimerization.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15|15 B3.1

Cellular Component: extracellular space; focal adhesion; leading edge; mitochondrion; nucleus; perinuclear region of cytoplasm; postsynaptic density; protein complex; vesicle

Molecular Function: cadherin binding; identical protein binding; protein binding; protein complex binding; protein domain specific binding; protein kinase binding; RNA binding; transcription factor binding; ubiquitin protein ligase binding

Biological Process: establishment of Golgi localization; histamine secretion by mast cell; protein targeting; protein targeting to mitochondrion; response to drug
Research Articles on Ywhaz
1. When taken together these findings demonstrate novel roles of 14-3-3zeta in the regulation of glucose homeostasis and suggest that modulating 14-3-3zeta levels in intestinal L cells may have beneficial metabolic effects through GLP-1-dependent mechanisms.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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