Full Product Name
KLK13 Polyclonal Antibody
Product Synonym Names
KLK13
Product Gene Name
anti-KLK13 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 19; NC_000019.9 (51559463..51568367, complement). Location: 19q13.33
3D Structure
ModBase 3D Structure for Q5BQ95
Specificity
KLK13 [This rabbit antibody recognizes aa 262-277 of human KLK13 (also known as KLK-L4), one of the many kallikrein serine proteases associated with carcinogenesis.]
This antibody recognizes the gene product hk13 of human KLK13 (also known as KLK-L4), one of the many kallikrein serine proteases associated with carcinogenesis. KLK13 is upregulated by steroid hormones and is expressed in prostate, salivary gland, breast, and testis.
Form/Format
100 ug affinity-purified antibody in PBS, pH 7.4.
Antigen
Peptide corresponding to aa 262-277 of human KLK13 protein.
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -70 degree C. Avoid multiple freeze thaw cycles.
Other Notes
Small volumes of anti-KLK13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-KLK13 antibody
Cancer Research Products
Applications Tested/Suitable for anti-KLK13 antibody
Immunoblot
Application Notes for anti-KLK13 antibody
Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 30 kD is detected.
NCBI/Uniprot data below describe general gene information for KLK13. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056411.1
[Other Products]
NCBI GenBank Nucleotide #
NM_015596.1
[Other Products]
UniProt Primary Accession #
Q5BQ95
[Other Products]
UniProt Related Accession #
Q5BQ95; Q5BQ97; Q5BQ99; Q86VI7; Q86VI8; Q9UKR3[Other Products]
Molecular Weight
10,685 Da[Similar Products]
NCBI Official Full Name
kallikrein-13
NCBI Official Synonym Full Names
kallikrein-related peptidase 13
NCBI Official Symbol
KLK13??[Similar Products]
NCBI Official Synonym Symbols
KLKL4; KLK-L4; DKFZp586J1923
??[Similar Products]
NCBI Protein Information
kallikrein-13; kallikrein 13; kallikrein-like gene 4; kallikrein-like protein 4
UniProt Protein Name
Kallikrein 13 splice variant 7
Protein Family
Kallikrein
UniProt Gene Name
KLK13??[Similar Products]
UniProt Entry Name
Q5BQ95_HUMAN
NCBI Summary for KLK13
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq]
UniProt Comments for KLK13
KLK13: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Protein type: Secreted, signal peptide; EC 3.4.21.-; Secreted; Vesicle; Protease
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: extracellular space; cytoplasm; extracellular region; secretory granule
Molecular Function: protein binding; hydrolase activity; serine-type endopeptidase activity
Biological Process: protein processing; proteolysis
Research Articles on KLK13
1. This is the first study disclosing the possible clinical utility of KLK13 as a new tumor biomarker capable of predicting a favorable outcome for gastric cancer patients.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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