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15-lipoxygenase, ELISA Kit

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產(chǎn)品名稱: 15-lipoxygenase, ELISA Kit
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15-lipoxygenase, ELISA Kit


15-lipoxygenase, ELISA Kit  的詳細(xì)介紹
Product Name

15-lipoxygenase (15-LO/LOX), ELISA Kit

Full Product Name

Canine 15-lipoxygenase (15-LO/LOX) ELISA Kit

Product Gene Name

15-LO/LOX elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
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OMIM
152392
Species Reactivity
Canine
Preparation and Storage
Store all reagents at 2-8 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of 15-LO/LOX elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for 15-LO/LOX purchase
MBS2603991 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 15-lipoxygenase (15-LO/LOX) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing 15-LO/LOX. The ELISA analytical biochemical technique of the MBS2603991 kit is based on 15-LO/LOX antibody-15-LO/LOX antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect 15-LO/LOX antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, 15-LO/LOX. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for 15-LO/LOX. It may not necessarily be applicable to this product.
NCBI GI #
307135
NCBI GeneID
246
NCBI Accession #
AAA36182.1 [Other Products]
UniProt Secondary Accession #
Q8N6R7; Q99657; A8K2P4; B7ZA11[Other Products]
UniProt Related Accession #
P16050[Other Products]
Molecular Weight
70,108 Da
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NCBI Official Full Name
15-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Official Symbol
ALOX15??[Similar Products]
NCBI Official Synonym Symbols
12-LOX; 15LOX-1; 15-LOX-1
??[Similar Products]
NCBI Protein Information
arachidonate 15-lipoxygenase
UniProt Protein Name
Arachidonate 15-lipoxygenase
UniProt Synonym Protein Names
12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type (EC:1.13.11.31
UniProt Gene Name
ALOX15??[Similar Products]
UniProt Synonym Gene Names
LOG15; 12-LOX??[Similar Products]
UniProt Entry Name
LOX15_HUMAN
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UniProt Comments for 15-LO/LOX
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.

Protein type: Motility/polarity/chemotaxis; Oxidoreductase; Lipid Metabolism - linoleic acid; EC 1.13.11.33; Lipid Metabolism - arachidonic acid; EC 1.13.11.31

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: cytosol; extrinsic to internal side of plasma membrane; lipid particle; membrane; plasma membrane

Molecular Function: arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin A3 synthase activity; hepoxilin-epoxide hydrolase activity; iron ion binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding

Biological Process: apoptotic cell clearance; arachidonic acid metabolic process; bone mineralization; hepoxilin biosynthetic process; inflammatory response; leukotriene metabolic process; lipoxygenase pathway; negative regulation of adaptive immune response; ossification; phosphatidylethanolamine biosynthetic process; positive regulation of actin filament polymerization; positive regulation of heterotypic cell-cell adhesion; wound healing
Research Articles on 15-LO/LOX
1. limiting ALOX15 expression by AMPK may promote an anti-inflammatory phenotype of IL-4-stimulated human macrophages
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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