C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; Cxcr2; Il8rb; CD182

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

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Small volumes of Cxcr2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2882900 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-X-C chemokine receptor type 2 (Cxcr2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Cxcr2. The ELISA analytical biochemical technique of the MBS2882900 kit is based on Cxcr2 antibody-Cxcr2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Cxcr2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Cxcr2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

40,532 Da

chemokine (C-X-C motif) receptor 2

C-X-C chemokine receptor type 2

C-X-C chemokine receptor type 2

Il8rb; CXC-R2; CXCR-2; IL-8R B??[Similar Products]

CXCR2_RAT

chemokine receptor that binds Il8, GRO/MGSA and neutrophil activating peptide-2; involved in the inflammatory response [RGD, Feb 2006]

IL-8R B: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Receptor, cytokine; GPCR, family 1; Membrane protein, integral

Cellular Component: cell surface; cytosol; integral to membrane; intracellular; mast cell granule; membrane; plasma membrane

Molecular Function: C-X-C chemokine receptor activity; chemokine receptor activity; interleukin-8 binding; interleukin-8 receptor activity; signal transducer activity

Biological Process: acute inflammatory response to antigenic stimulus; cell surface receptor linked signal transduction; cellular defense response; chemotaxis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); midbrain development; negative regulation of apoptosis; negative regulation of neutrophil apoptosis; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of leukocyte chemotaxis; positive regulation of vascular permeability; receptor internalization; signal transduction

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