C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; CDw128b; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2; CXCR2; IL8RB; CD182

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

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Small volumes of CXCR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2880182 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-X-C chemokine receptor type 2 (CXCR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CXCR2. The ELISA analytical biochemical technique of the MBS2880182 kit is based on CXCR2 antibody-CXCR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

40,759 Da

C-X-C chemokine receptor type 2

IL8RB; CXC-R2; CXCR-2; IL-8R B??[Similar Products]

CXCR2_HUMAN

IL-8R B: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cell surface; cytosol; integral to plasma membrane; intracellular; mast cell granule; membrane; plasma membrane

Molecular Function: C-X-C chemokine receptor activity; interleukin-8 binding; interleukin-8 receptor activity; protein binding; signal transducer activity

Biological Process: acute inflammatory response to antigenic stimulus; cell surface receptor linked signal transduction; cellular defense response; chemotaxis; dendritic cell chemotaxis; elevation of cytosolic calcium ion concentration; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; midbrain development; negative regulation of neutrophil apoptosis; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of vascular permeability; receptor internalization; signal transduction

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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