Recombinant C-X-C chemokine receptor type 2 (Cxcr2); C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor High affinity interleukin-8 receptor B; IL-8R B CD_antigen= CD182

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 9; NC_005108.3 (81193442..81199814). Location: 9q33

E Coli or Yeast or Baculovirus or Mammalian Cell

>=90% (lot specific)

Liquid containing glycerol

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterile filter available upon request.

Low endotoxin available upon request.

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Small volumes of Cxcr2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

40,532 Da[Similar Products]

chemokine (C-X-C motif) receptor 2

C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; chemokine (C-X-C) receptor 2; interleukin 8 receptor, beta; high affinity interleukin-8 receptor B

C-X-C chemokine receptor type 2

Il8rb; CXC-R2; CXCR-2; IL-8R B??[Similar Products]

CXCR2_RAT

chemokine receptor that binds Il8, GRO/MGSA and neutrophil activating peptide-2; involved in the inflammatory response [RGD, Feb 2006]

IL-8R B: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; Receptor, cytokine; GPCR, family 1

Cellular Component: mast cell granule; cell surface; membrane; integral to membrane; plasma membrane; intracellular

Molecular Function: signal transducer activity; interleukin-8 receptor activity; chemokine receptor activity; interleukin-8 binding; C-X-C chemokine receptor activity

Biological Process: neutrophil chemotaxis; neutrophil activation; positive regulation of leukocyte chemotaxis; signal transduction; chemotaxis; positive regulation of vascular permeability; negative regulation of neutrophil apoptosis; G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; receptor internalization; positive regulation of cell proliferation; midbrain development; cellular defense response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); acute inflammatory response to antigenic stimulus; negative regulation of apoptosis

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