Product Name
C-X-C chemokine receptor type 2 (Cxcr2), Recombinant Protein
Full Product Name
Recombinant Mouse C-X-C chemokine receptor type 2 (Cxcr2), partial
Product Gene Name
Cxcr2 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P35343
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Cxcr2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Cxcr2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_034039.1
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NCBI GenBank Nucleotide #
NM_009909.3
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UniProt Primary Accession #
P35343
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UniProt Secondary Accession #
Q53X27[Other Products]
UniProt Related Accession #
P35343[Other Products]
Molecular Weight
40,425 Da
NCBI Official Full Name
C-X-C chemokine receptor type 2
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 2
NCBI Official Symbol
Cxcr2??[Similar Products]
NCBI Official Synonym Symbols
CD128; IL8RA; Il8rb; CDw128; Cmkar2; Gpcr16; IL-8Rh; IL-8rb; mIL-8RH
??[Similar Products]
NCBI Protein Information
C-X-C chemokine receptor type 2
UniProt Protein Name
C-X-C chemokine receptor type 2
UniProt Synonym Protein Names
GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; CD_antigen: CD182
Protein Family
C-X-C chemokine receptor
UniProt Gene Name
Cxcr2??[Similar Products]
UniProt Synonym Gene Names
Cmkar2; Gpcr16; Il8rb; CXC-R2; CXCR-2; IL-8R B??[Similar Products]
UniProt Comments for Cxcr2
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Research Articles on Cxcr2
1. these data provide novel insight into a dynamic IL-17A-CXCR2-neutrophil axis during acute segmented filamentous bacteria colonization and demonstrate a central role for neutrophils in limiting segmented filamentous bacteria expansion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
