Product Name
C-X-C chemokine receptor type 2 (CXCR2), Recombinant Protein
Full Product Name
Recombinant Dog C-X-C chemokine receptor type 2 (CXCR2)
Product Synonym Names
Recombinant C-X-C chemokine receptor type 2 (CXCR2); C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor High affinity interleukin-8 receptor B; IL-8R B CD_antigen= CD182
Product Gene Name
CXCR2 recombinant protein
[Similar Products]
Product Synonym Gene Name
CXCR2; IL8RB[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MEYINWDNYS LEDLFGDIDN YTYNTEMPII PADSAPCRPE SLDINKYAVV VIYVLVFVLN LLGNSLVIMV VLYSRVSHSV TDVYLLNLAI ADLLFALTLP IWAVSKVKGW IFGTPLCKIV SLLKEVNFYS GILLLASISM DRYLAIVHAT RRLTQKKHWV KFICLGIWAL SLILSLPIFV FRRAINPPYS SPVCYEDMGT NTTKLRIVMR ALPQTFGFIV PLMIMLFCYG LTLRTLFEAH MGQKHRAMRV IFAVVLVFLL CWLPYNLVAD TLMRLQAIEE TCQRRNDIGR ALDATEILGF FHSCLNPLIY AFIGQKFRHG LLKIMAFHGL ISKEYLPKDS RPSFVGSSSA NTSTTF
Chromosome Location
Chromosome: 37; NC_006619.3 (24839130..24844541). Location: chromosome: 37
3D Structure
ModBase 3D Structure for O97571
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CXCR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CXCR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001003151.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001003151.1
[Other Products]
UniProt Primary Accession #
O97571
[Other Products]
UniProt Related Accession #
O97571[Other Products]
Molecular Weight
40,505 Da[Similar Products]
NCBI Official Full Name
C-X-C chemokine receptor type 2
NCBI Official Symbol
CXCR2??[Similar Products]
NCBI Official Synonym Symbols
IL8RB
??[Similar Products]
NCBI Protein Information
C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; interleukin-8 receptor, beta; high affinity interleukin-8 receptor B
UniProt Protein Name
C-X-C chemokine receptor type 2
UniProt Synonym Protein Names
GRO/MGSA receptor; High affinity interleukin-8 receptor B
Protein Family
C-X-C chemokine receptor
UniProt Gene Name
CXCR2??[Similar Products]
UniProt Synonym Gene Names
IL8RB; CXC-R2; CXCR-2; IL-8R B??[Similar Products]
UniProt Entry Name
CXCR2_CANFA
UniProt Comments for CXCR2
Function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Post-translational modification: Phosphorylated upon ligand binding; which is required for desensitization
By similarity.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Research Articles on CXCR2
1. Interleukin-8 expression associated with canine mammary tumors
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
