Product Name
5-hydroxytryptamine receptor 1D (Htr1d), Recombinant Protein
Full Product Name
Recombinant Rat 5-hydroxytryptamine receptor 1D (Htr1d)
Product Gene Name
Htr1d recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-374aa; full length protein
Sequence
MSLPNQSLEG LPQEASNRSL NATGAWDPEV LQALRISLVV VLSIITLATV LSNAFVLTTI LLTKKLHTPA NYLIGSLATT DLLVSILVMP ISIAYTTTRT WNFGQILCDI WVSSDITCCT ASILHLCVIA LDRYWAITDA LEYSKRRTAG HAAAMIAAVW AISICISIPP LFWRQATAHE EMSDCLVNTS QISYTIYSTC GAFYIPSILL IILYGRIYVA ARSRILNPPS LYGKRFTTAQ LITGSAGSSL CSLNPSLHES HTHTVGSPLF FNQVKIKLAD SILERKRISA ARERKATKTL GIILGAFIIC WLPFFVVSLV LPICRDSCWI HPALFDFFTW LGYLNSLINP VIYTVFNEDF RQAFQRVVHF RKAS
3D Structure
ModBase 3D Structure for P28565
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Htr1d recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Htr1d recombinant protein
Transmembrane Protein
Application Notes for Htr1d recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Htr1d. It may not necessarily be applicable to this product.
NCBI Accession #
NP_036984.1
[Other Products]
NCBI GenBank Nucleotide #
NM_012852.1
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UniProt Primary Accession #
P28565
[Other Products]
UniProt Related Accession #
P28565[Other Products]
Molecular Weight
41,540 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1D
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 1D
NCBI Official Symbol
Htr1d??[Similar Products]
NCBI Official Synonym Symbols
5HT1D
??[Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1D
UniProt Protein Name
5-hydroxytryptamine receptor 1D
UniProt Synonym Protein Names
Serotonin receptor 1D
Protein Family
5-hydroxytryptamine receptor
UniProt Gene Name
Htr1d??[Similar Products]
UniProt Synonym Gene Names
5-HT-1D; 5-HT1D??[Similar Products]
UniProt Entry Name
5HT1D_RAT
NCBI Summary for Htr1d
G-protein coupled receptor for serotonin; found in nociceptors throughout the body [RGD, Feb 2006]
UniProt Comments for Htr1d
5-HT(1D): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: integral to plasma membrane
Molecular Function: serotonin binding; serotonin receptor activity
Biological Process: G-protein signaling, adenylate cyclase inhibiting pathway; intestine smooth muscle contraction; regulation of behavior; regulation of locomotion; response to toxin; serotonin receptor signaling pathway; synaptic transmission; vasoconstriction
Research Articles on Htr1d
1. 5-HTB/D receptors have a role in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
