Product Name
xeroderma pigmentosum, complementation group C (XPC), ELISA Kit
Full Product Name
Mouse DNA repair protein complementing XP-C cells, XPC ELISA Kit
Product Synonym Names
Mouse DNA repair protein complementing XP-C cells (XPC) ELISA kit; RAD4; XP3; XPCC; xeroderma pigmentosum group C protein; xeroderma pigmentosum; complementation group C
Product Gene Name
XPC elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P51612
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of XPC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for XPC purchase
MBS9316874 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the xeroderma pigmentosum, complementation group C (XPC) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing XPC. The ELISA analytical biochemical technique of the MBS9316874 kit is based on XPC antibody-XPC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect XPC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, XPC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for XPC. It may not necessarily be applicable to this product.
NCBI Accession #
NP_033557.2
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NCBI GenBank Nucleotide #
NM_009531.2
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UniProt Primary Accession #
P51612
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UniProt Secondary Accession #
P54732; Q3TKI2; Q920M1; Q9DBW7[Other Products]
UniProt Related Accession #
P51612[Other Products]
Molecular Weight
104,522 Da
NCBI Official Full Name
DNA repair protein complementing XP-C cells homolog
NCBI Official Synonym Full Names
xeroderma pigmentosum, complementation group C
NCBI Official Symbol
Xpc??[Similar Products]
NCBI Protein Information
DNA repair protein complementing XP-C cells homolog; p125; xeroderma pigmentosum group C-complementing protein homolog
UniProt Protein Name
DNA repair protein complementing XP-C cells homolog
UniProt Synonym Protein Names
Xeroderma pigmentosum group C-complementing protein homolog; p125
Protein Family
DNA repair protein
UniProt Gene Name
Xpc??[Similar Products]
UniProt Entry Name
XPC_MOUSE
UniProt Comments for XPC
XPC: a probable nuclear protein involved in DNA excision repair. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C.
Protein type: DNA repair, damage
Cellular Component: cytoplasm; plasma membrane; nucleolus; nucleus
Molecular Function: DNA binding; damaged DNA binding; single-stranded DNA binding
Biological Process: nucleotide-excision repair, DNA damage recognition; intra-S DNA damage checkpoint; nucleotide-excision repair; DNA repair; response to DNA damage stimulus; response to UV-B
Research Articles on XPC
1. Study indicates that Xpc(-/-) mice have an increased mutational load upon induction of oxidative stress. The effect of non-functional XPC in vivo appears to have implications in mutagenesis, which can contribute to the carcinogenesis process.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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