Glycogen phosphorylase; liver form; Pygl; Lgp; 2.4.1.1

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of Pygl elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9426192 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glycogen phosphorylase (Pygl) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Pygl. The ELISA analytical biochemical technique of the MBS9426192 kit is based on Pygl antibody-Pygl antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Pygl antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Pygl. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

97,483 Da

glycogen phosphorylase L

glycogen phosphorylase, liver form

Glycogen phosphorylase, liver form

Lgp??[Similar Products]

catalyzes the rate-limiting step of glycogen catabolism [RGD, Feb 2006]

PYGL: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Defects in PYGL are the cause of glycogen storage disease type 6 (GSD6). A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected. Belongs to the glycogen phosphorylase family.

Protein type: Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.1; Transferase

Chromosomal Location of Human Ortholog: 6q24

Cellular Component: cytoplasm

Molecular Function: AMP binding; ATP binding; bile acid binding; carbohydrate binding; drug binding; glycogen phosphorylase activity; protein homodimerization activity; purine binding; pyridoxal phosphate binding; vitamin binding

Biological Process: 5-phosphoribose 1-diphosphate biosynthetic process; glucose homeostasis; glycogen catabolic process; glycogen metabolic process

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