Full Product Name
ATX10 Polyclonal Antibody
Product Synonym Names
Ataxin-10; Brain protein E46 homolog; Spinocerebellar ataxia type 10 protein; ATXN10; SCA10
Product Gene Name
anti-ATX10 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UBB4
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 10-90
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-ATX10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ATX10 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ATX10 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for ATX10. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001161093.1
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NCBI GenBank Nucleotide #
NM_001167621.1
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UniProt Primary Accession #
Q9UBB4
[Other Products]
UniProt Secondary Accession #
O14998; O15009; Q6I9X4; A6NLC4; B4DG05[Other Products]
UniProt Related Accession #
Q9UBB4[Other Products]
NCBI Official Full Name
ataxin-10 isoform 2
NCBI Official Synonym Full Names
ataxin 10
NCBI Official Symbol
ATXN10??[Similar Products]
NCBI Official Synonym Symbols
E46L; SCA10; HUMEEP
??[Similar Products]
NCBI Protein Information
ataxin-10
UniProt Protein Name
Ataxin-10
UniProt Synonym Protein Names
Brain protein E46 homolog; Spinocerebellar ataxia type 10 protein
UniProt Gene Name
ATXN10??[Similar Products]
UniProt Synonym Gene Names
SCA10??[Similar Products]
NCBI Summary for ATX10
This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jul 2016]
UniProt Comments for ATX10
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
Research Articles on ATX10
1. Polymorphism in ATXN10 gene is associated with spinocerebellar ataxia type 10.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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