Product Name
ADP-ribosyl cyclase 1 (CD38), Recombinant Protein
Full Product Name
Recombinant Rabbit ADP-ribosyl cyclase 1 (CD38), partial
Product Gene Name
CD38 recombinant protein
[Similar Products]
Product Synonym Gene Name
CD38[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
43-298
Sequence
LTWRQSSM GATDHVSAIV LGRCLTYTRN MHPELRNQDC KKILNTFTSA FVSKDPCNIT KEDYQPLIDL VTQTVPCNKT LFWSRSKELA HQYSGIQKEM FTLEDTLLGY IADNLVWCGD PRTSEVKEEF CPYRNENCSS TATSVFWTVV SQKFAESACG TVYVMLNGSR TTAFSKASTF GSVEVFNLHP DRVHTLHAWV MHDIGGVERD SCLGSSIKEL KSIVNQRNIS FFCQDDYRPA RFVQCVRHPE HPSCSVLM
3D Structure
ModBase 3D Structure for Q9MZ03
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CD38 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CD38 recombinant protein
CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling.
NCBI/Uniprot data below describe general gene information for CD38. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001076152.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001082683.1
[Other Products]
UniProt Primary Accession #
Q9MZ03
[Other Products]
UniProt Related Accession #
Q9MZ03[Other Products]
Molecular Weight
33,637 Da
NCBI Official Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
NCBI Official Symbol
CD38??[Similar Products]
NCBI Official Synonym Symbols
ADPRC 1
??[Similar Products]
NCBI Protein Information
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
UniProt Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
UniProt Synonym Protein Names
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20); 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD_antigen: CD38
Protein Family
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
UniProt Gene Name
CD38??[Similar Products]
UniProt Synonym Gene Names
ADPRC 1; cADPr hydrolase 1??[Similar Products]
UniProt Comments for CD38
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity.
Research Articles on CD38
1. Data, including data from studies on cells from knockout mice, suggest that intracellular CD38 contributes to NAADP production and cADPR production in cardiomyocytes; membrane fractions from wildtype but not CD38-/- mouse hearts support NAADP and cADPR synthesis; CD38 may be associated with sarcoplasmic reticulum of cardiomyocytes. (NAADP = nicotinate adenine dinucleotide phosphate; cADPR = cyclic ADP-ribose)
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
