Product Name
ELMD2 (ELMOD2), Blocking Peptide
Full Product Name
ELMD2 Antibody (C-term) Blocking peptide
Product Synonym Names
ELMO domain-containing protein 2; ELMOD2
Product Gene Name
ELMOD2 blocking peptide
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Antibody/Peptide Pairs
ELMD2 peptide (MBS9218779) is used for blocking the activity of ELMD2 antibody (MBS9211518)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8IZ81
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Tissue Location
Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of ELMOD2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ELMOD2 blocking peptide
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
NCBI/Uniprot data below describe general gene information for ELMOD2. It may not necessarily be applicable to this product.
NCBI Accession #
Q8IZ81.1
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UniProt Primary Accession #
Q8IZ81
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UniProt Secondary Accession #
B2R712; D3DNZ0[Other Products]
UniProt Related Accession #
Q8IZ81[Other Products]
Molecular Weight
34,961 Da
NCBI Official Full Name
ELMO domain-containing protein 2
NCBI Official Synonym Full Names
ELMO domain containing 2
NCBI Official Symbol
ELMOD2??[Similar Products]
NCBI Official Synonym Symbols
9830169G11Rik
??[Similar Products]
NCBI Protein Information
ELMO domain-containing protein 2
UniProt Protein Name
ELMO domain-containing protein 2
Protein Family
ELMO domain-containing protein
UniProt Gene Name
ELMOD2??[Similar Products]
UniProt Entry Name
ELMD2_HUMAN
NCBI Summary for ELMOD2
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
UniProt Comments for ELMOD2
ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
Chromosomal Location of Human Ortholog: 4q31.1
Cellular Component: membrane
Molecular Function: GTPase activator activity
Biological Process: regulation of defense response to virus
Disease: Pulmonary Fibrosis, Idiopathic
Research Articles on ELMOD2
1. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity.
Precautions
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Disclaimer
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