Product Name
ELMOD2, Polyclonal Antibody
Full Product Name
ELMOD2 Antibody
Product Synonym Names
9830169G11Rik; MGC10084
Product Gene Name
anti-ELMOD2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of ELMOD2
Calculated Molecular Weight: 293aa; 32kd
Observed Molecular Weight: 32kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82878
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ELMOD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ELMOD2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ELMOD2 antibody
WB: 1:500-1:5000
IHC: 1:50-1:200
Testing Data of anti-ELMOD2 antibody
NCBI/Uniprot data below describe general gene information for ELMOD2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_714913.1
[Other Products]
NCBI GenBank Nucleotide #
NM_153702.3
[Other Products]
UniProt Secondary Accession #
B2R712; D3DNZ0[Other Products]
UniProt Related Accession #
Q8IZ81[Other Products]
Molecular Weight
34,961 Da
NCBI Official Full Name
ELMO domain-containing protein 2
NCBI Official Synonym Full Names
ELMO/CED-12 domain containing 2
NCBI Official Symbol
ELMOD2??[Similar Products]
NCBI Official Synonym Symbols
9830169G11Rik
??[Similar Products]
NCBI Protein Information
ELMO domain-containing protein 2; ELMO domain containing 2
UniProt Protein Name
ELMO domain-containing protein 2
Protein Family
ELMO domain-containing protein
UniProt Gene Name
ELMOD2??[Similar Products]
UniProt Entry Name
ELMD2_HUMAN
NCBI Summary for ELMOD2
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
UniProt Comments for ELMOD2
ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
Chromosomal Location of Human Ortholog: 4q31.1
Cellular Component: cytoskeleton; membrane
Molecular Function: GTPase activator activity
Biological Process: regulation of defense response to virus; defense response to virus; phagocytosis; positive regulation of GTPase activity
Disease: Pulmonary Fibrosis, Idiopathic
Research Articles on ELMOD2
1. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity.
Precautions
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Disclaimer
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