Product Name
ELMOD2, Polyclonal Antibody
Full Product Name
ELMOD2 Antibody
Product Gene Name
anti-ELMOD2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Specificity
Human and predicted against mouse and rat.
Purity/Purification
Affinity purified
Form/Format
PBS, pH 7.4 with 0.02% Sodium Azide
Concentration
1.0 mg/ml (lot specific)
Immunogen Type
Recombinant Protein
Immunogen Description
Rabbit polyclonal ELMOD2 (1) antibody was raised against a recombinate human ELMOD2 protein 21-207aa (BC015168).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Other Notes
Small volumes of anti-ELMOD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-ELMOD2 antibody
Total protein Ab
Applications Tested/Suitable for anti-ELMOD2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ELMOD2 antibody
ELISA: 1:20000-1:80000
WB: 1:500-1:1000
IHC: 1:100-1:500
Testing Data of anti-ELMOD2 antibody
Testing Data of anti-ELMOD2 antibody
NCBI/Uniprot data below describe general gene information for ELMOD2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_714913.1
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NCBI GenBank Nucleotide #
NM_153702.3
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UniProt Secondary Accession #
B2R712; D3DNZ0[Other Products]
UniProt Related Accession #
Q8IZ81[Other Products]
Molecular Weight
34,961 Da
NCBI Official Full Name
ELMO domain-containing protein 2
NCBI Official Synonym Full Names
ELMO/CED-12 domain containing 2
NCBI Official Symbol
ELMOD2??[Similar Products]
NCBI Official Synonym Symbols
9830169G11Rik
??[Similar Products]
NCBI Protein Information
ELMO domain-containing protein 2
UniProt Protein Name
ELMO domain-containing protein 2
Protein Family
ELMO domain-containing protein
UniProt Gene Name
ELMOD2??[Similar Products]
UniProt Entry Name
ELMD2_HUMAN
NCBI Summary for ELMOD2
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
UniProt Comments for ELMOD2
ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
Chromosomal Location of Human Ortholog: 4q31.1
Cellular Component: cytoskeleton; membrane
Molecular Function: GTPase activator activity
Biological Process: regulation of defense response to virus; defense response to virus; phagocytosis; positive regulation of GTPase activity
Disease: Pulmonary Fibrosis, Idiopathic
Research Articles on ELMOD2
1. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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