Product Name
Calbindin (CALB1), Recombinant Protein
Popular Item
Full Product Name
Recombinant Chicken Calbindin (CALB1)
Product Gene Name
CALB1 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-262. Full length of the mature protein.
Sequence
TAETHLQGVE ISAAQFFEIW HHYDSDGNGY MDGKELQNFI QELQQARKKA GLDLTPEMKA FVDQYGKATD GKIGIVELAQ VLPTEENFLL FFRCQQLKSS EDFMQTWRKY DSDHSGFIDS EELKSFLKDL LQKANKQIED SKLTEYTEIM LRMFDANNDG KLELTELARL LPVQENFLIK FQGVKMCAKE FNKAFEMYDQ DGNGYIDENE LDALLKDLCE KNKKELDINN LATYKKSIMA LSDGGKLYRA ELALILCAEE N
3D Structure
ModBase 3D Structure for P04354
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CALB1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CALB1 recombinant protein
Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted.
NCBI/Uniprot data below describe general gene information for CALB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_990844.1
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NCBI GenBank Nucleotide #
NM_205513.1
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UniProt Primary Accession #
P04354
[Other Products]
UniProt Related Accession #
P04354[Other Products]
Molecular Weight
30,167 Da
NCBI Official Full Name
calbindin
NCBI Official Synonym Full Names
calbindin 1
NCBI Official Symbol
CALB1??[Similar Products]
NCBI Protein Information
calbindin
UniProt Protein Name
Calbindin
UniProt Synonym Protein Names
Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type
UniProt Gene Name
CALB1??[Similar Products]
UniProt Comments for CALB1
Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
Research Articles on CALB1
1. The vector-based transient receptor potential vanilloid 6(TRPV6)-shRNA can efficiently suppress the mRNA and protein expression of TRPV6 in chicken osteoblasts, and TRPV6 regulates the expression of calbindin-D28K during Ca2+ transport.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
