Product Name
Claudin-16 (CLDN16), Recombinant Protein
Full Product Name
Recombinant Bovine Claudin-16 (CLDN16)
Product Gene Name
CLDN16 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-254aa; full length protein
Sequence
MGPGLAASHV SFPDSLLAKM RDLLQYVACF FAFFSAGFLV VATWTDCWMV NADDSLEVST KCRGLWWECV TNAFDGIRTC DEYDSILAEH SLKLVVTRAL MITADILAGF GFITLLLGLD CVKFLPDEPY IKVRISFVAG TTLLIAGAPG IIGSVWYAVD VYVERSSLVL HNIFLGIQYK FGWSCWLGMA GSLGCFLAGA ILTCCLYLFK DVGPERSYPY STRKAYSTTA VSMPRSHAIP RTQTAKMYAV DTRV
3D Structure
ModBase 3D Structure for Q9XT98
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CLDN16 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for CLDN16 recombinant protein
Transmembrane Protein
Application Notes for CLDN16 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for CLDN16. It may not necessarily be applicable to this product.
NCBI Accession #
NP_776944.1
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NCBI GenBank Nucleotide #
NM_174519.2
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UniProt Primary Accession #
Q9XT98
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UniProt Related Accession #
Q9XT98[Other Products]
Molecular Weight
27,992 Da
NCBI Official Full Name
claudin-16
NCBI Official Symbol
CLDN16??[Similar Products]
NCBI Protein Information
claudin-16
UniProt Protein Name
Claudin-16
UniProt Gene Name
CLDN16??[Similar Products]
UniProt Synonym Gene Names
CL-16??[Similar Products]
UniProt Entry Name
CLD16_BOVIN
UniProt Comments for CLDN16
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors ().
Research Articles on CLDN16
1. or =50 cells) were present.">Claudin-16 sequences were not usually amplified from a small number of sperm cells (< or =10 cells) but claudin-16 DNA sequences were occasionally detected when a large number of sperm cells (> or =50 cells) were present.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
