Product Name
DBNL, Polyclonal Antibody
Popular Item
Full Product Name
DBNL Polyclonal Antibody
Product Synonym Names
ABP1; HIP-55; HIP55; SH3P7
Product Gene Name
anti-DBNL antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI DHHIQGQGLS GQGLCARALY DYQAA
3D Structure
ModBase 3D Structure for Q9UJU6
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human DBNL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Golgi apparatus membrane, Peripheral membrane protein, cell cortex, clathrin-coated vesicle membrane, cytoskeleton, cytosol, lamellipodium, podosome, ruffle, synapse
Positive Samples
HeLa, MCF-7, Jurkat, K-562, Mouse brain, Mouse thymus, Mouse spleen, Mouse testis, Rat heart
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-DBNL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-DBNL antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-DBNL antibody
Western Blot (WB)
Application Notes for anti-DBNL antibody
WB: 1:500 - 1:2000
Western Blot (WB) of anti-DBNL antibody
Western blot analysis of extracts of various cell lines, using DBNL antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 1s.
NCBI/Uniprot data below describe general gene information for DBNL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001014436.1
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NCBI GenBank Nucleotide #
NM_001014436.2
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UniProt Primary Accession #
Q9UJU6
[Other Products]
UniProt Secondary Accession #
P84070; Q6IAI8; Q96F30; Q96K74; Q9HBN8; Q9NR72; A4D2I9; B4DDP6; B4DEM2; C9J7P1[Other Products]
UniProt Related Accession #
Q9UJU6[Other Products]
Molecular Weight
Calculated: 37kDa; 43kDa; 48kDa; 49kDa
Observed: 56kDa
NCBI Official Full Name
drebrin-like protein isoform b
NCBI Official Synonym Full Names
drebrin like
NCBI Official Symbol
DBNL??[Similar Products]
NCBI Official Synonym Symbols
ABP1; HIP55; SH3P7; HIP-55
??[Similar Products]
NCBI Protein Information
drebrin-like protein
UniProt Protein Name
Drebrin-like protein
UniProt Synonym Protein Names
Cervical SH3P7; Cervical mucin-associated protein; Drebrin-F; HPK1-interacting protein of 55 kDa; HIP-55; SH3 domain-containing protein 7
Protein Family
Drebrin-like protein
UniProt Gene Name
DBNL??[Similar Products]
UniProt Synonym Gene Names
CMAP; SH3P7; HIP-55??[Similar Products]
UniProt Comments for DBNL
Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.
Research Articles on DBNL
1. findings show that mAbp1 and FHL2 are novel binding partners that differentially regulate Rho GTPase signaling and MTLn3 breast cancer cell invasion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
