Product Name
CYBRD1, Polyclonal Antibody
Full Product Name
CYBRD1 Antibody - C-terminal region
Product Gene Name
anti-CYBRD1 antibody
[Similar Products]
Product Synonym Gene Name
DCYTB; FRRS3; CYB561A2[Similar Products]
Antibody/Peptide Pairs
CYBRD1 peptide (MBS3246543) is used for blocking the activity of CYBRD1 antibody (MBS3221817)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: PNGGTEQGAR GSMPAYSGNN MDKSDSELNS EVAARKRNLA LDEAGQRSTM
3D Structure
ModBase 3D Structure for Q53TN4
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CYBRD1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CYBRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CYBRD1 antibody
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption.
Product Categories/Family for anti-CYBRD1 antibody
Polyclonal; Cell Biology; Tissue Specific & Cell Marker;
Applications Tested/Suitable for anti-CYBRD1 antibody
Western Blot (WB)
Western Blot (WB) of anti-CYBRD1 antibody
Host: Rabbit
Target Name: CYBRD1
Sample Tissue: Human Leiomyosarcoma Tumor lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for CYBRD1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001120855.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001127383.1
[Other Products]
UniProt Primary Accession #
Q53TN4
[Other Products]
UniProt Related Accession #
Q53TN4[Other Products]
NCBI Official Full Name
cytochrome b reductase 1 isoform 2
NCBI Official Synonym Full Names
cytochrome b reductase 1
NCBI Official Symbol
CYBRD1??[Similar Products]
NCBI Official Synonym Symbols
DCYTB; FRRS3; CYB561A2
??[Similar Products]
NCBI Protein Information
cytochrome b reductase 1
UniProt Protein Name
Cytochrome b reductase 1
UniProt Synonym Protein Names
Duodenal cytochrome b; Ferric-chelate reductase 3
Protein Family
Cytochrome b reductase
UniProt Gene Name
CYBRD1??[Similar Products]
UniProt Synonym Gene Names
DCYTB; FRRS3??[Similar Products]
UniProt Entry Name
CYBR1_HUMAN
NCBI Summary for CYBRD1
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]
UniProt Comments for CYBRD1
CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.-.-.-; Transporter; Transporter, ion channel; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Transporter, iron; Oxidoreductase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: brush border membrane; integral to membrane; plasma membrane
Molecular Function: oxidoreductase activity, oxidizing metal ions; metal ion binding; ferric-chelate reductase activity
Biological Process: cellular iron ion homeostasis; response to iron ion; transmembrane transport
Research Articles on CYBRD1
1. Studied the effect of iron supplements containing Lactobacillus plantarum on ferric iron metabolism and upregulation of duodenal cytochrome b ferric-chelate reductase 3 (DCTYB) in Caco-2 and HT-29 MTX cell lines.
Precautions
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Disclaimer
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