Product Name
CYBRD1, Polyclonal Antibody
Full Product Name
CYBRD1 Antibody - N-terminal region
Product Gene Name
anti-CYBRD1 antibody
[Similar Products]
Product Synonym Gene Name
DCYTB; FRRS3; CYB561A2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: GGHFFSTTQS PPATQGSTAA QRSTATQHST ATQSSTATQT SPVPLTPESP
3D Structure
ModBase 3D Structure for Q53TN4
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CYBRD1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CYBRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CYBRD1 antibody
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]
Product Categories/Family for anti-CYBRD1 antibody
Polyclonal; Cell Biology; Tissue Specific & Cell Marker;
Applications Tested/Suitable for anti-CYBRD1 antibody
Western Blot (WB)
Western Blot (WB) of anti-CYBRD1 antibody
Host: Rabbit
Target Name: CYBRD1
Sample Tissue: Human DLD1 Whole Cell lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for CYBRD1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001120855.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001127383.1
[Other Products]
UniProt Primary Accession #
Q53TN4
[Other Products]
UniProt Related Accession #
Q53TN4[Other Products]
NCBI Official Full Name
cytochrome b reductase 1 isoform 2
NCBI Official Synonym Full Names
cytochrome b reductase 1
NCBI Official Symbol
CYBRD1??[Similar Products]
NCBI Official Synonym Symbols
DCYTB; FRRS3; CYB561A2
??[Similar Products]
NCBI Protein Information
cytochrome b reductase 1
UniProt Protein Name
Cytochrome b reductase 1
UniProt Synonym Protein Names
Duodenal cytochrome b; Ferric-chelate reductase 3
Protein Family
Cytochrome b reductase
UniProt Gene Name
CYBRD1??[Similar Products]
UniProt Synonym Gene Names
DCYTB; FRRS3??[Similar Products]
UniProt Entry Name
CYBR1_HUMAN
NCBI Summary for CYBRD1
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]
UniProt Comments for CYBRD1
CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.-.-.-; Transporter; Transporter, ion channel; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Transporter, iron; Oxidoreductase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: brush border membrane; integral to membrane; plasma membrane
Molecular Function: oxidoreductase activity, oxidizing metal ions; metal ion binding; ferric-chelate reductase activity
Biological Process: cellular iron ion homeostasis; response to iron ion; transmembrane transport
Research Articles on CYBRD1
1. Studied the effect of iron supplements containing Lactobacillus plantarum on ferric iron metabolism and upregulation of duodenal cytochrome b ferric-chelate reductase 3 (DCTYB) in Caco-2 and HT-29 MTX cell lines.
Precautions
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Disclaimer
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