Human Cytochrome b reductase 1 (CYBRD1) ELISA kit; DCYTB; FLJ23462; FRRS3; duodenal cytochrome b; ferric-chelate reductase 3; cytochrome b reductase 1

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of CYBRD1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9325625 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cytochrome b reductase 1 (CYBRD1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CYBRD1. The ELISA analytical biochemical technique of the MBS9325625 kit is based on CYBRD1 antibody-CYBRD1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYBRD1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYBRD1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

31,641 Da

cytochrome b reductase 1

cytochrome b reductase 1; duodenal cytochrome b; ferric-chelate reductase 3; cytochrome b561 family, member A2

Cytochrome b reductase 1

DCYTB; FRRS3??[Similar Products]

CYBR1_HUMAN

This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]

CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, iron; Oxidoreductase; Transporter; EC 1.-.-.-; Motility/polarity/chemotaxis; Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: brush border membrane; plasma membrane; integral to membrane

Molecular Function: oxidoreductase activity, oxidizing metal ions; metal ion binding; ferric-chelate reductase activity

Biological Process: cellular iron ion homeostasis; transmembrane transport; response to iron ion

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