Neurabin-2; Neurabin-II; Neural tissue-specific F-actin-binding protein II; PP1bp134; Protein phosphatase 1 regulatory subunit 9B; Spinophilin; p130; Ppp1r9b

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of Ppp1r9b elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2880055 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neurabin-2 (Ppp1r9b) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Ppp1r9b. The ELISA analytical biochemical technique of the MBS2880055 kit is based on Ppp1r9b antibody-Ppp1r9b antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Ppp1r9b antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Ppp1r9b. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

89,646 Da

protein phosphatase 1, regulatory subunit 9B

neurabin-2

Neurabin-2

NEB2_RAT

interacts with protein phosphatase 1 and actin filaments; involved in regulation of synaptic transmission [RGD, Feb 2006]

Spinophilin: actin-binding regulatory subunit of protein phosphatase 1 (PP1). The actin-binding domain of spinophilin is necessary and sufficient for targeting of spinophilin to dendrites and dendritic spines. May play a role in establishing a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Interacts with p14-ARF. Contains one PDZ/DHR domain.

Protein type: Protein phosphatase, regulatory subunit; Adaptor/scaffold

Cellular Component: actin cytoskeleton; adherens junction; cell soma; cortical actin cytoskeleton; cytoplasm; dendritic spine; filopodium; growth cone; lamellipodium; neuron projection; nucleoplasm; nucleus; plasma membrane; postsynaptic density

Molecular Function: actin binding; actin filament binding; D2 dopamine receptor binding; kinase binding; protein binding; protein C-terminus binding; protein complex binding; protein kinase activity; protein phosphatase 1 binding; protein phosphatase inhibitor activity

Biological Process: actin filament depolymerization; actin filament organization; aging; calcium-mediated signaling; cell migration; cerebral cortex development; dendrite development; filopodium formation; hippocampus development; learning; male mating behavior; negative regulation of cell growth; negative regulation of phosphoprotein phosphatase activity; neurite development; protein amino acid phosphorylation; regulation of cell proliferation; regulation of protein amino acid phosphorylation; regulation of synaptic transmission; reproductive developmental process; response to amino acid stimulus; response to amphetamine; response to drug; response to estradiol stimulus; response to nicotine; response to organic cyclic substance; response to organic nitrogen; response to steroid hormone stimulus

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