Product Name
10 kDa heat shock (CH10), Recombinant Protein
Full Product Name
Recombinant Human 10 kDa heat shock protein, mitochondrial
Product Synonym Names
10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
Product Gene Name
CH10 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Full Length, 2-102aa
3D Structure
ModBase 3D Structure for P61604
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Other Notes
Small volumes of CH10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CH10 recombinant protein
Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
NCBI/Uniprot data below describe general gene information for CH10. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002148.1
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NCBI GenBank Nucleotide #
NM_002157.2
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UniProt Primary Accession #
P61604
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UniProt Secondary Accession #
O95421; Q04984; Q53X54; Q9UDH0[Other Products]
UniProt Related Accession #
P61604[Other Products]
NCBI Official Full Name
10 kDa heat shock protein, mitochondrial
NCBI Official Synonym Full Names
heat shock protein family E (Hsp10) member 1
NCBI Official Symbol
HSPE1??[Similar Products]
NCBI Official Synonym Symbols
EPF; CPN10; GROES; HSP10
??[Similar Products]
NCBI Protein Information
10 kDa heat shock protein, mitochondrial
UniProt Protein Name
10 kDa heat shock protein, mitochondrial
UniProt Synonym Protein Names
10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
Protein Family
10 kDa heat shock protein
UniProt Gene Name
HSPE1??[Similar Products]
UniProt Synonym Gene Names
Hsp10; CPN10; EPF??[Similar Products]
NCBI Summary for CH10
This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
UniProt Comments for CH10
HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 2q33.1
Cellular Component: membrane; mitochondrial matrix; mitochondrion
Molecular Function: chaperone binding; metal ion binding; protein binding; RNA binding; unfolded protein binding
Biological Process: chaperone cofactor-dependent protein folding; osteoblast differentiation; protein folding; response to unfolded protein
Research Articles on CH10
1. EPF induces the differentiation of regulatory T cells and increases their immunosuppressive activities.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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