Full Product Name
HES7 Antibody, Biotin conjugated
Product Synonym Names
Transcription factor HES-7; hHes7; Class B basic helix-loop-helix protein 37; bHLHb37; Hairy and enhancer of split 7; bHLH factor Hes7; HES7; BHLHB37
Product Gene Name
anti-HES7 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BYE0
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Transcription factor HES-7 protein (127-192AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-HES7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HES7 antibody
Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity).
Product Categories/Family for anti-HES7 antibody
Epigenetics and Nuclear Signaling; Developmental
biology; Stem cells
Applications Tested/Suitable for anti-HES7 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for HES7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001159439.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001165967.1
[Other Products]
UniProt Primary Accession #
Q9BYE0
[Other Products]
UniProt Secondary Accession #
F8VPC9[Other Products]
UniProt Related Accession #
Q9BYE0[Other Products]
Molecular Weight
25,280 Da
NCBI Official Full Name
transcription factor HES-7 isoform 1
NCBI Official Synonym Full Names
hes family bHLH transcription factor 7
NCBI Official Symbol
HES7??[Similar Products]
NCBI Official Synonym Symbols
SCDO4; bHLHb37
??[Similar Products]
NCBI Protein Information
transcription factor HES-7
UniProt Protein Name
Transcription factor HES-7
UniProt Synonym Protein Names
Class B basic helix-loop-helix protein 37; bHLHb37; Hairy and enhancer of split 7; bHLH factor Hes7
Protein Family
Transcription factor
UniProt Gene Name
HES7??[Similar Products]
UniProt Synonym Gene Names
BHLHB37; hHes7; bHLHb37??[Similar Products]
NCBI Summary for HES7
This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
UniProt Comments for HES7
Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation ().
Research Articles on HES7
1. an Indian family links Coats plus syndrome and dextrocardia with a homozygous novel CTC1 and a rare HES7 variation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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